Kisspeptin Signaling in Reproductive Biology

Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood.  This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet know...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Kauffman, Alexander S. (Editor,, Smith, Jeremy T. (Editor,
Format: Electronic eBook
Published: New York, NY : Springer New York : Imprint: Springer, 2013.
Edition:1st ed. 2013.
Series:Advances in Experimental Medicine and Biology, 784
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Table of Contents:
  • Part One: Kisspeptin Signaling in vivo and in vitro
  • Kisspeptin: Past, Present and Prologue
  • Structure, Synthesis, and Phylogeny of Kisspeptin and its Receptor
  • Neuroanatomy of the Kisspeptin Signaling System in Mammals: Comparative and Developmental Aspects
  • The Effects of Kisspeptin on Gonadotropin Release in Non-Human Mammals
  • Effects of Kisspeptin on Hormone Secretion in Humans
  • Kisspeptin Excitation of GnRH Neurons
  • Molecular Biology of the Kisspeptin Receptor: Signaling, Function, and Mutations
  • Kisspeptin Antagonists
  • Kisspeptin and Clinical Disorders
  • Beyond the GnRH Axis: Kisspeptin Regulation of the Oxytocin System in Pregnancy and Lactation
  • Part Two: Development and Regulation of Kisspeptin Neurons
  • The Development of Kisspeptin Circuits in the Mammalian Brain
  • Kisspeptin and Puberty in Mammals
  • Sex Steroid Regulation of Kisspeptin Circuits
  • Kisspeptin and GnRH Pulse Generation
  • Interactions between Kisspeptins and Neurokinin B
  • Electrophysiology of Kisspeptin Neurons
  • Metabolic Regulation of Kisspeptin
  • Circadian Regulation of Kisspeptin in Female Reproductive Functioning
  • Kisspeptin and Seasonality of Reproduction
  • Stress Regulation of Kisspeptin in the Modulation of Reproductive Function
  • Effects of Environmental Endocrine Disruptors and Phytoestrogens on the Kisspeptin System
  • Model Systems for Studying Kisspeptin Signaling: Mice and Cells
  • Index.