Mass Spectrometry in Metabolomics Methods and Protocols /

Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Raftery, Daniel. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronic eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Humana, 2014.
Edition:1st ed. 2014.
Series:Methods in Molecular Biology, 1198
Subjects:
Online Access:https://doi.org/10.1007/978-1-4939-1258-2
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Table of Contents:
  • Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges
  • Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry
  • LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations
  • Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry
  • Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling
  • Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection
  • Analysis of Mouse Liver Metabolites by GC×GC–TOF MS
  • Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry
  • Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry
  • Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis
  • Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS
  • Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM
  • Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics
  • Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry
  • Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species
  • Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis
  • Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs)
  • Metabolite Profiling by Direct Analysis in Real Time Mass Spectrometry
  • Analysis of Dried Blood Spots using DESI Mass Spectrometry
  • DESI-MS Imaging of Lipids and Metabolites from Biological Samples
  • Metabolic Imaging using Nanostructure-Initiator Mass Spectrometry (NIMS)
  • Statistical Analysis and Modeling of Mass Spectrometry-Based Metabolomics Data.