Carbohydrate-Based Vaccines Methods and Protocols /

 This volume summarizes current cutting-edge methods related to carbohydrate-based vaccines, from the identification of a suitable carbohydrate antigen via the preparation of glycoconjugate vaccines to the characterization of vaccine candidates for their use in pre-clinical and clinical studies. Wri...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Lepenies, Bernd. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronic eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Humana, 2015.
Edition:1st ed. 2015.
Series:Methods in Molecular Biology, 1331
Subjects:
Online Access:https://doi.org/10.1007/978-1-4939-2874-3
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Table of Contents:
  • Carbohydrate-based Vaccines: An Overview
  • Glycans as Vaccine Antigens and Adjuvants: Immunological Considerations
  • The Glycan Array Platform as a Tool to Identify Carbohydrate Antigens
  • Antibody-carbohydrate Recognition from Docked Ensembles using the AutoMap Procedure
  • Generation of Monoclonal Antibodies against Defined Oligosaccharide Antigens
  • Murine Whole-Blood Opsonophagocytosis Assay to Evaluate Protection by Antibodies Raised Against Encapsulated Extracellular Bacteria
  • Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility
  • N-Glycosylation Fingerprinting of Viral Glycoproteins by xCGE-LIF
  • Temporary Conversion of Protein Amino Groups To Azides: A Synthetic Strategy For Glycoconjugate Vaccines
  • Gold Nanoparticles as Carriers For Synthetic Glycoconjugate Vaccines
  • Identification and Characterization of Carbohydrate-Based Adjuvants
  • Characterization of Carbohydrate Vaccines by NMR Spectroscopy Francesco Berti and Neil Ravenscroft
  • Characterisation of Capsular Polysaccharides and Their Glycoconjugates by Hydrodynamic Methods
  • Glycoconjugate Vaccines: The Regulatory Framework.