Single Nucleotide Polymorphisms Methods and Protocols /
Single nucleotide polymorphisms (SNPs) have become the markers of choice in elucidating the relationship between DNA sequence variation and susceptibility to disease and have clearly become the focus of the next phase of the human genome project. In Single Nucleotide Polymorphisms: Methods and Proto...
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| Formato: | Recurso Eletrônico livro eletrônico |
| Idioma: | English |
| Publicado em: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2003.
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| Edição: | 1st ed. 2003. |
| coleção: | Methods in Molecular Biology,
212 |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1385/1592593275 |
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Sumário:
- SNPs: Why Do We Care?
- Denaturing High-Performance Liquid Chromatography
- SNP Detection and Allele Frequency Determination by SSCP
- Conformation-Sensitive Gel Electrophoresis
- Detection of Mutations in DNA by Solid-Phase Chemical Cleavage Method
- SNP Discovery by Direct DNA Sequencing
- Computational SNP Discovery in DNA Sequence Data
- Genotyping SNPs With Molecular Beacons
- SNP Genotyping by the ?’-Nuclease Reaction
- Genotyping SNPs by Minisequencing Primer Extension Using Oligonucleotide Microarrays
- Quantitative Analysis of SNPs in Pooled DNA Samples by Solid-Phase Minisequencing
- Homogeneous Primer Extension Assay With Fluorescence Polarization Detection
- Pyrosequencing for SNP Genotyping
- Homogeneous Allele-Specific PCR in SNP Genotyping
- Oligonucleotide Ligation Assay
- Invader Assay for SNP Genotyping
- MALDI-TOF Mass Spectrometry-Based SNP Genotyping.