Cardiac Cell and Gene Transfer
Cellular and gene-based experimental techniques promise powerful new therapeutic agents for the remediation of both acquired and inherited cardiovascular disease. In Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications, Joseph M. Metzger and a panel of leading scientific experts d...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2003.
|
| Edition: | 1st ed. 2003. |
| Series: | Methods in Molecular Biology,
219 |
| Subjects: | |
| Online Access: | https://doi.org/10.1385/159259350X |
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| 245 | 1 | 0 | |a Cardiac Cell and Gene Transfer |h [electronic resource] / |c edited by Joseph M. Metzger. |
| 250 | |a 1st ed. 2003. | ||
| 264 | 1 | |a Totowa, NJ : |b Humana Press : |b Imprint: Humana, |c 2003. | |
| 300 | |a XI, 253 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 490 | 1 | |a Methods in Molecular Biology, |x 1064-3745 ; |v 219 | |
| 505 | 0 | |a Vectors for Cardiac Gene Transfer -- Adenoviral Vectors -- Gutted Adenoviral Vectors for Gene Transfer to Muscle -- Dual Vector Expansion of the Recombinant AAV Packaging Capacity -- Lentivirus Vector-Mediated Gene Transfer to Cardiomyocytes -- Cell Transfer to Myocardium -- Cell Therapy in the Heart -- Cardiac Cell Transplantation -- Cell Grafting for Cardiac Repair -- Vectors for Cardiac Gene Transfer -- Suppressor tRNAs -- Antisense Oligonucleotides -- Theoretical and Technical Considerations for Gene Transfer into Vascularized Cardiac Transplants -- Isolation, Culture, and Gene Transfer of Adult Canine Cardiac Myocytes -- Myofilament Protein Phosphorylation by PKC in Genetically Engineered Adult Cardiac Myocytes -- In Vivo Cardiac Gene Transfer -- Embryonic and Neonatal Cardiac Gene Transfer In Vivo -- Efficient Viral Gene Transfer to Rodent Hearts In Vivo -- Direct Gene Transfer to the Adult Rodent Myocardium In Vivo -- Adenovirus-Mediated Gene Transfer to Cardiac Myocytes In Vivo Using Catheter-Based Procedures -- Coronary Perfusion Cocktails for In Vivo Gene Transfer -- Modification of In Vivo Cardiac Performance by Intracoronary Gene Transfer of ?-Adrenergic Receptor Signaling Components -- Protocols for Hemodynamic Assessment of Transgenic Mice In Vivo. | |
| 520 | |a Cellular and gene-based experimental techniques promise powerful new therapeutic agents for the remediation of both acquired and inherited cardiovascular disease. In Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications, Joseph M. Metzger and a panel of leading scientific experts detail many novel techniques and strategies for the cellular and genetic modification of heart function. These highly experienced authors provide step-by-step protocols for vector production and purification, for gene and cell delivery techniques, and for physiological assessment in vivo and in vitro. Timely, authoritative, and state-of-the-art, Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications constitutes an invaluable guide to all the new cellular and gene-based technologies needed by basic and clinical investigators working to illuminate today's unanswered questions about heart disease and ultimately to improve the heart performance in all their patients. | ||
| 650 | 0 | |a Cardiology. | |
| 650 | 1 | 4 | |a Cardiology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H33037 |
| 700 | 1 | |a Metzger, Joseph M. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781617372926 |
| 776 | 0 | 8 | |i Printed edition: |z 9780896039940 |
| 776 | 0 | 8 | |i Printed edition: |z 9781489938091 |
| 830 | 0 | |a Methods in Molecular Biology, |x 1064-3745 ; |v 219 | |
| 856 | 4 | 0 | |u https://doi.org/10.1385/159259350X |
| 912 | |a ZDB-2-PRO | ||
| 950 | |a Springer Protocols (Springer-12345) | ||