Mammalian Chromosome Engineering Methods and Protocols /
The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the med...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2011.
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| Edition: | 1st ed. 2011. |
| Series: | Methods in Molecular Biology,
738 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-1-61779-099-7 |
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Table of Contents:
- Developing Extrachromosomal Gene Expression Vector Technologies: An Overview
- High Capacity Extrachromosomal Gene Expression Vectors
- Naturally Occurring Minichromosome Platforms in Chromosome Engineering: An Overview
- Chromosome Transfer Via Cell Fusion
- Insertional Engineering of Chromosomes with Sleeping Beauty Transposition: An Overview
- Rodent Transgenesis Mediated by a Novel Hyperactive Sleeping Beauty Transposon System
- Construction and Use of a Bottom-Up HAC Vector for Transgene Expression
- De novo Generation of Satellite DNA-Based Artificial Chromosomes by Induced Large-Scale Amplification
- Downstream Bioengineering of ACE Chromosomes for Incorporation of Site-Specific Recombination Cassettes
- Chromosome Engineering with Lambda-Integrase Mediated Recombination System: The ACE System
- Dendrimer Mediated Transfer of Engineered Chromosomes
- Engineered Chromosomes in Transgenics
- Transfer of Stem Cells Carrying Engineered Chromosomes with XY Clone Laser System
- Mammalian Artificial Chromosomes and Clinical Applications for Genetic Modification of Stem Cells: An Overview
- Engineered Mammalian Chromosomes in Cellular Protein Production: Future Prospects.