RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes.  However, a long series of striking discoveries,...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Gorodkin, Jan. (Editor, http://id.loc.gov/vocabulary/relators/edt), Ruzzo, Walter L. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronic eBook
Language:English
Published: Totowa, NJ : Humana Press : Imprint: Humana, 2014.
Edition:1st ed. 2014.
Series:Methods in Molecular Biology, 1097
Subjects:
Online Access:https://doi.org/10.1007/978-1-62703-709-9
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Table of Contents:
  • Concepts and Introduction to RNA Bioinformatics
  • The Principles of RNA Structure Architecture
  • The Determination of RNA Folding Nearest Neighbor Parameters
  • Energy Directed RNA Structure Prediction
  • Introduction to Stochastic Context Free Grammars
  • An Introduction to RNA Databases
  • Energy-based RNA Consensus Secondary Structure Prediction in Multiple Sequence Alignments
  • SCFGs in RNA Secondary Structure Prediction: A Hands-on Approach
  • Annotating Functional RNAs in Genomes using Infernal
  • Class-specific Prediction of ncRNAs
  • Abstract Shape Analysis of RNA
  • Introduction to RNA Secondary Structure Comparison
  • RNA Structural Alignments, Part I: Sankoff Based Approaches for Structural Alignments
  • RNA Structural Alignments, Part II: Non-Sankoff Approaches for Structural Alignments
  • De novo Discovery of Structured ncRNA Motifs in Genomic Sequences.,- Phylogeny and Evolution of RNA Structure
  • The Art of Editing RNA Structural Alignments
  • Automated Modeling of RNA 3D Structure
  • Computational Prediction of RNA-RNA Interactions
  • Computational Prediction of microRNA Genes
  • MicroRNA Target Finding by Comparative Genomics
  • Bioinformatics of siRNA Design
  • RNA-protein Interactions: An Overview.