Untranslated Gene Regions and Other Non-coding Elements Regulation of Eukaryotic Gene Expression /
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitat...
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| Main Authors: | , , |
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| Corporate Author: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Basel :
Springer Basel : Imprint: Springer,
2013.
|
| Edition: | 1st ed. 2013. |
| Series: | SpringerBriefs in Biochemistry and Molecular Biology,
|
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-0348-0679-4 |
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| LEADER | 03600nam a22005655i 4500 | ||
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| 001 | 978-3-0348-0679-4 | ||
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| 024 | 7 | |a 10.1007/978-3-0348-0679-4 |2 doi | |
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| 100 | 1 | |a Barrett, Lucy W. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Untranslated Gene Regions and Other Non-coding Elements |h [electronic resource] : |b Regulation of Eukaryotic Gene Expression / |c by Lucy W. Barrett, Sue Fletcher, Steve D. Wilton. |
| 250 | |a 1st ed. 2013. | ||
| 264 | 1 | |a Basel : |b Springer Basel : |b Imprint: Springer, |c 2013. | |
| 300 | |a VIII, 56 p. 2 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a SpringerBriefs in Biochemistry and Molecular Biology, |x 2211-9353 | |
| 505 | 0 | |a Introduction -- Promoter -- 5’ Untranslated Region -- Structure -- Intronic Regions -- 3’ Untranslated Region -- Non-coding RNAs -- Conclusion. | |
| 520 | |a There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution. | ||
| 650 | 0 | |a Animal genetics. | |
| 650 | 0 | |a Plant genetics. | |
| 650 | 0 | |a Medical genetics. | |
| 650 | 0 | |a Nucleic acids. | |
| 650 | 1 | 4 | |a Animal Genetics and Genomics. |0 https://scigraph.springernature.com/ontologies/product-market-codes/L32030 |
| 650 | 2 | 4 | |a Plant Genetics and Genomics. |0 https://scigraph.springernature.com/ontologies/product-market-codes/L32020 |
| 650 | 2 | 4 | |a Gene Function. |0 https://scigraph.springernature.com/ontologies/product-market-codes/B12030 |
| 650 | 2 | 4 | |a Nucleic Acid Chemistry. |0 https://scigraph.springernature.com/ontologies/product-market-codes/L14011 |
| 700 | 1 | |a Fletcher, Sue. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 700 | 1 | |a Wilton, Steve D. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
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| 776 | 0 | 8 | |i Printed edition: |z 9783034806800 |
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| 830 | 0 | |a SpringerBriefs in Biochemistry and Molecular Biology, |x 2211-9353 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-0348-0679-4 |
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| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||