Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases
This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed ‘amyloid’. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alz...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edition: | 1st ed. 2015. |
| Series: | Advances in Experimental Medicine and Biology,
863 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-319-18365-7 |
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| 245 | 1 | 0 | |a Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases |h [electronic resource] / |c edited by Neville Vassallo. |
| 250 | |a 1st ed. 2015. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2015. | |
| 300 | |a VII, 163 p. 41 illus., 26 illus. in color. |b online resource. | ||
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| 490 | 1 | |a Advances in Experimental Medicine and Biology, |x 0065-2598 ; |v 863 | |
| 505 | 0 | |a Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease -- Alzheimer’s disease, Drosophila melanogaster and Polyphenols -- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer’s disease -- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines -- Tea Polyphenols in Parkinson’s disease -- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism. | |
| 520 | |a This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed ‘amyloid’. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer’s disease-related dementia and Parkinson’s disease, as well as other less prevalent conditions like Huntington’s disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry. | ||
| 650 | 0 | |a Neurochemistry. | |
| 650 | 0 | |a Nutrition . | |
| 650 | 0 | |a Neurology . | |
| 650 | 0 | |a Pharmacy. | |
| 650 | 1 | 4 | |a Neurochemistry. |0 https://scigraph.springernature.com/ontologies/product-market-codes/B18010 |
| 650 | 2 | 4 | |a Nutrition. |0 https://scigraph.springernature.com/ontologies/product-market-codes/C18000 |
| 650 | 2 | 4 | |a Neurology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H36001 |
| 650 | 2 | 4 | |a Pharmacy. |0 https://scigraph.springernature.com/ontologies/product-market-codes/F00008 |
| 700 | 1 | |a Vassallo, Neville. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
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| 776 | 0 | 8 | |i Printed edition: |z 9783319183664 |
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| 776 | 0 | 8 | |i Printed edition: |z 9783319359502 |
| 830 | 0 | |a Advances in Experimental Medicine and Biology, |x 0065-2598 ; |v 863 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-319-18365-7 |
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| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||