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Free-Radical-Induced DNA Damage and Its Repair A Chemical Perspective /

Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals hav...

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Bibliographic Details
Main Author: Sonntag, Clemens. (Author, http://id.loc.gov/vocabulary/relators/aut)
Corporate Author: SpringerLink (Online service)
Format: Electronic eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2006.
Edition:1st ed. 2006.
Subjects:
Biochemistry.
Cell biology.
Life sciences.
Molecular biology.
Oncology  .
Organic chemistry.
Biochemistry, general.
Cell Biology.
Life Sciences, general.
Molecular Medicine.
Oncology.
Organic Chemistry.
Online Access:https://doi.org/10.1007/3-540-30592-0
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Table of Contents:
  • Formation of Reactive Free Radicals in an Aqueous Environment
  • The Hydroxyl Radical
  • Hydrogen Atom and Hydrated Electron
  • Inorganic Radicals
  • Carbon-Centered Radicals
  • Heteroatom-Centered Radicals
  • Peroxyl Radicals
  • Polymer Radicals
  • Nucleobases, Nucleosides and Nucleotides
  • Polynucleotides and Single-Stranded DNA Fragments
  • DNA and Double-Stranded Oligonucleotides
  • Methods.

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