Free-Radical-Induced DNA Damage and Its Repair A Chemical Perspective /
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals hav...
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| Autor principal: | |
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| Autor Corporativo: | |
| Formato: | Recurso Eletrônico livro eletrônico |
| Idioma: | English |
| Publicado em: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2006.
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| Edição: | 1st ed. 2006. |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/3-540-30592-0 |
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Sumário:
- Formation of Reactive Free Radicals in an Aqueous Environment
- The Hydroxyl Radical
- Hydrogen Atom and Hydrated Electron
- Inorganic Radicals
- Carbon-Centered Radicals
- Heteroatom-Centered Radicals
- Peroxyl Radicals
- Polymer Radicals
- Nucleobases, Nucleosides and Nucleotides
- Polynucleotides and Single-Stranded DNA Fragments
- DNA and Double-Stranded Oligonucleotides
- Methods.