Myeloproliferative Neoplasms Critical Concepts and Management /
Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelo...
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2012.
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| Edition: | 1st ed. 2012. |
| Series: | Hematologic Malignancies,
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| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-642-24989-1 |
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| LEADER | 03680nam a22005295i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-24989-1 | ||
| 003 | DE-He213 | ||
| 005 | 20200706035546.0 | ||
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| 024 | 7 | |a 10.1007/978-3-642-24989-1 |2 doi | |
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| 245 | 1 | 0 | |a Myeloproliferative Neoplasms |h [electronic resource] : |b Critical Concepts and Management / |c edited by Tiziano Barbui, Ayalew Tefferi. |
| 250 | |a 1st ed. 2012. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2012. | |
| 300 | |a VIII, 240 p. 22 illus., 13 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 490 | 1 | |a Hematologic Malignancies, |x 2197-9766 | |
| 505 | 0 | |a Biology -- Gerneral Issues in the Management of MPNs -- Specific Issues of Treatment in PV and ET -- Treatment of PMF -- Research Issues and Perspectives. | |
| 520 | |a Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. A number of important questions regarding the diagnosis, prognosis, and treatment of these diseases have arisen following the discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative MPNs. This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field. | ||
| 650 | 0 | |a Hematology. | |
| 650 | 0 | |a Internal medicine. | |
| 650 | 0 | |a Oncology . | |
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| 650 | 2 | 4 | |a Internal Medicine. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H33002 |
| 650 | 2 | 4 | |a Oncology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H33160 |
| 700 | 1 | |a Barbui, Tiziano. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Tefferi, Ayalew. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
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| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642249884 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642249907 |
| 776 | 0 | 8 | |i Printed edition: |z 9783662520277 |
| 830 | 0 | |a Hematologic Malignancies, |x 2197-9766 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-642-24989-1 |
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| 950 | |a Medicine (SpringerNature-11650) | ||
| 950 | |a Medicine (R0) (SpringerNature-43714) | ||