Small Molecules in Oncology
Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targe...
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| Other Authors: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2014.
|
| Edition: | 2nd ed. 2014. |
| Series: | Recent Results in Cancer Research,
201 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-642-54490-3 |
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| LEADER | 03350nam a22005175i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-54490-3 | ||
| 003 | DE-He213 | ||
| 005 | 20200703223020.0 | ||
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| 020 | |a 9783642544903 |9 978-3-642-54490-3 | ||
| 024 | 7 | |a 10.1007/978-3-642-54490-3 |2 doi | |
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| 245 | 1 | 0 | |a Small Molecules in Oncology |h [electronic resource] / |c edited by Uwe M. Martens. |
| 250 | |a 2nd ed. 2014. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2014. | |
| 300 | |a XVI, 417 p. 46 illus., 26 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Recent Results in Cancer Research, |x 0080-0015 ; |v 201 | |
| 505 | 0 | |a Imatinib Mesylate -- Erlotinib -- Axitinib (AG-013736) -- Lapatinib -- Sorafenib -- Sunitinib -- Dasatinib -- Nilotinib -- Bosutinib -- Decitabine -- Azacytidine/Azacitidine -- Bortezomib -- Temsirolimus -- Danusertib -- Vismodegib -- Everolimus -- Vemurafenib -- Vandetanib -- Trametinib -- Dabrafenib -- Ponatinib -- Regorafenib -- Cabozantinib -- Revlimid -- Ibrutinib -- Qizartinib -- Ruxolitinib -- Carfilzomib -- Afitinib. | |
| 520 | |a Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book, written by acknowledged experts, discusses in detail the most recent developments in targeted cancer therapy using small molecules. A wide range of small molecules is covered, including, in addition to tyrosine kinase inhibitors, mTOR, proteasome, and multikinase inhibitors, among others. For each molecule, aspects such as chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. | ||
| 650 | 0 | |a Oncology . | |
| 650 | 0 | |a Hematology. | |
| 650 | 0 | |a Cancer research. | |
| 650 | 1 | 4 | |a Oncology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H33160 |
| 650 | 2 | 4 | |a Hematology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H3307X |
| 650 | 2 | 4 | |a Cancer Research. |0 https://scigraph.springernature.com/ontologies/product-market-codes/B11001 |
| 700 | 1 | |a Martens, Uwe M. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642544897 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642544910 |
| 776 | 0 | 8 | |i Printed edition: |z 9783662519257 |
| 830 | 0 | |a Recent Results in Cancer Research, |x 0080-0015 ; |v 201 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-642-54490-3 |
| 912 | |a ZDB-2-SME | ||
| 912 | |a ZDB-2-SXM | ||
| 950 | |a Medicine (SpringerNature-11650) | ||
| 950 | |a Medicine (R0) (SpringerNature-43714) | ||