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Chemokine Biology - Basic Research and Clinical Application Vol. 2: Pathophysiology of Chemokines /

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, a...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Neote, Kuldeep. (Editor, http://id.loc.gov/vocabulary/relators/edt), Letts, L. Gordon. (Editor, http://id.loc.gov/vocabulary/relators/edt), Moser, Bernhard. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronic eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2007.
Edition:1st ed. 2007.
Series:Progress in Inflammation Research,
Subjects:
Immunology.
Pharmacology.
Cell biology.
Pharmacology/Toxicology.
Cell Biology.
Online Access:https://doi.org/10.1007/978-3-7643-7437-2
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Table of Contents:
  • Chemokines in animal disease models
  • Chemokines in animal models of inflammation
  • Autoimmune diseases
  • Chemokines in allergic responses: eosinophils, basophils, mast cells
  • Chemokines as drug targets
  • Chemokines as drug targets
  • Screening and characterization of cyclic pentapeptide CXCR4 antagonists/inverse agonists using a pheromone responsive reporter gene in Saccharomyces cerevisiae: Utility of G protein coupled receptor constitutively active mutants
  • Antagonists of CXCR3: a review of current progress
  • IL-8 receptor antagonist: basic research and clinical utility
  • Current status of CCR1 antagonists in clinical trials
  • Small molecule CCR2 antagonists
  • Chemokine axes in hematopoietic stem cell mobilization
  • CCR5 antagonists: from discovery to clinical efficacy.

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