Non-viral Gene Therapy Gene Design and Delivery /
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| Autres auteurs: | , , |
| Format: | Électronique eBook |
| Langue: | English |
| Publié: |
Tokyo :
Springer Japan : Imprint: Springer,
2005.
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| Édition: | 1st ed. 2005. |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1007/4-431-27879-6 |
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| LEADER | 05101nam a22005775i 4500 | ||
|---|---|---|---|
| 001 | 978-4-431-27879-5 | ||
| 003 | DE-He213 | ||
| 005 | 20200705085040.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100301s2005 ja | s |||| 0|eng d | ||
| 020 | |a 9784431278795 |9 978-4-431-27879-5 | ||
| 024 | 7 | |a 10.1007/4-431-27879-6 |2 doi | |
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| 245 | 1 | 0 | |a Non-viral Gene Therapy |h [electronic resource] : |b Gene Design and Delivery / |c edited by Kazunari Taira, Kazunori Kataoka, Takuro Niidome. |
| 250 | |a 1st ed. 2005. | ||
| 264 | 1 | |a Tokyo : |b Springer Japan : |b Imprint: Springer, |c 2005. | |
| 300 | |a XII, 487 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Molecules for Gene Therapy -- Recent Progress in Non-viral Gene Delivery -- Physical Chemistry of DNA-Carrier Complexes -- Liposomes -- Polymeric Gene Carriers -- Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers -- Chitosan -- Dendrimers as DNA Carriers -- Use of Synthetic Peptides for Non-viral Gene Delivery -- An Oligonucleotide Carrier Based on ?-1,3-Glucans -- Biological and Chemical Hybrid Vectors -- Controlled Gene Delivery -- Pharmacokinetics of Gene Delivery in Cells -- Active DNA Release from Complexes -- Controlled Release of DNA Using Thermoresponsive Polymers -- Active Transport of Exogenous Genes into the Nucleus -- Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation -- Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer -- Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery -- In Vivo Gene Transfer by Ligand-Modified Gene Carriers -- Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy -- Gene Transfer and Target Diseases -- Clinical Trials Using Non-viral Gene Delivery Systems -- Current Protocols of Gene Delivery -- Evaluation of Size and Zeta Potential of DNA/Carrier Complexes -- Observation of DNA/Carrier Complexes Under Fluorescence Microscopy -- Synthesis of Chemically Modified Chitosan and a Study of Its Gene Transfection Efficiency -- Newly Designed DNA Fragments for Gene Correction -- Evaluation of Gene Expression In Vivo After Intravenous and Intraportal Administration of Lipoplexes -- Evaluation by Southern Blot Hybridization of DNA Administered with a Gene Carrier to Organs -- Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes -- Gateway RNAi -- Design of Genes Based on Current RNA Technology -- Design of Intracellularly Active Ribozymes and siRNAs -- RNAi-Based Inhibition Specific for Mutant Alleles in Autosomal Dominant Diseases: Sequence-Dependent and -Independent Discrimination of Mutant and Wild-Type Alleles by siRNA -- In Vivo RNA Interference: Another Tool in the Box? -- Suppression of Gene Expression via Chromatin Remodeling and the siRNA-Induced Silencing of Transcription -- Intracellular Delivery of Nucleic Acids: Differences Between Transfection and siFection Reflect Differences Between DNA and RNA, and Between Oligodeoxynucleotides and Oligonucleotides -- In Vivo Antitumor Activity of a New Cationic Liposome siRNA Complex -- Enhancing RNAi with Synthetic RNA Duplexes. | |
| 650 | 0 | |a Cell biology. | |
| 650 | 0 | |a Biotechnology. | |
| 650 | 0 | |a Molecular biology. | |
| 650 | 0 | |a Genetic engineering. | |
| 650 | 0 | |a Biochemical engineering. | |
| 650 | 0 | |a Medical biochemistry. | |
| 650 | 1 | 4 | |a Cell Biology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/L16008 |
| 650 | 2 | 4 | |a Biotechnology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/C12002 |
| 650 | 2 | 4 | |a Molecular Medicine. |0 https://scigraph.springernature.com/ontologies/product-market-codes/B1700X |
| 650 | 2 | 4 | |a Genetic Engineering. |0 https://scigraph.springernature.com/ontologies/product-market-codes/C12037 |
| 650 | 2 | 4 | |a Biochemical Engineering. |0 https://scigraph.springernature.com/ontologies/product-market-codes/C12029 |
| 650 | 2 | 4 | |a Medical Biochemistry. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H35005 |
| 700 | 1 | |a Taira, Kazunari. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Kataoka, Kazunori. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Niidome, Takuro. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9784431800217 |
| 776 | 0 | 8 | |i Printed edition: |z 9784431547389 |
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| 856 | 4 | 0 | |u https://doi.org/10.1007/4-431-27879-6 |
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| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||