Non-viral Gene Therapy Gene Design and Delivery /
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| Ente Autore: | |
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| Altri autori: | , , |
| Natura: | Elettronico eBook |
| Lingua: | English |
| Pubblicazione: |
Tokyo :
Springer Japan : Imprint: Springer,
2005.
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| Edizione: | 1st ed. 2005. |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1007/4-431-27879-6 |
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Sommario:
- Molecules for Gene Therapy
- Recent Progress in Non-viral Gene Delivery
- Physical Chemistry of DNA-Carrier Complexes
- Liposomes
- Polymeric Gene Carriers
- Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers
- Chitosan
- Dendrimers as DNA Carriers
- Use of Synthetic Peptides for Non-viral Gene Delivery
- An Oligonucleotide Carrier Based on ?-1,3-Glucans
- Biological and Chemical Hybrid Vectors
- Controlled Gene Delivery
- Pharmacokinetics of Gene Delivery in Cells
- Active DNA Release from Complexes
- Controlled Release of DNA Using Thermoresponsive Polymers
- Active Transport of Exogenous Genes into the Nucleus
- Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation
- Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer
- Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery
- In Vivo Gene Transfer by Ligand-Modified Gene Carriers
- Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy
- Gene Transfer and Target Diseases
- Clinical Trials Using Non-viral Gene Delivery Systems
- Current Protocols of Gene Delivery
- Evaluation of Size and Zeta Potential of DNA/Carrier Complexes
- Observation of DNA/Carrier Complexes Under Fluorescence Microscopy
- Synthesis of Chemically Modified Chitosan and a Study of Its Gene Transfection Efficiency
- Newly Designed DNA Fragments for Gene Correction
- Evaluation of Gene Expression In Vivo After Intravenous and Intraportal Administration of Lipoplexes
- Evaluation by Southern Blot Hybridization of DNA Administered with a Gene Carrier to Organs
- Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes
- Gateway RNAi
- Design of Genes Based on Current RNA Technology
- Design of Intracellularly Active Ribozymes and siRNAs
- RNAi-Based Inhibition Specific for Mutant Alleles in Autosomal Dominant Diseases: Sequence-Dependent and -Independent Discrimination of Mutant and Wild-Type Alleles by siRNA
- In Vivo RNA Interference: Another Tool in the Box?
- Suppression of Gene Expression via Chromatin Remodeling and the siRNA-Induced Silencing of Transcription
- Intracellular Delivery of Nucleic Acids: Differences Between Transfection and siFection Reflect Differences Between DNA and RNA, and Between Oligodeoxynucleotides and Oligonucleotides
- In Vivo Antitumor Activity of a New Cationic Liposome siRNA Complex
- Enhancing RNAi with Synthetic RNA Duplexes.