Pharmacogenetics of CYP450A, ABCB1, ABCC2, SLCO1B3 gene polymorphisms and plasma alpha-1-acid glycoprotein level on nonhaematological adverse events of docetaxel in Malaysian breast cancer patients
Docetaxel is an antitubulin chemotherapeutic agent approved for the treatment of breast, lung, ovarian and non-hormonal dependent prostate cancers. However, the success of this drug is limited by adverse events (AEs), the severity of which ranges from tolerable to life threatening. Tapering the dose...
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| Formato: | Thesis |
| Idioma: | English |
| Publicado: |
2015
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| Acceso en liña: | http://ethesis.upm.edu.my/id/eprint/12108/1/FPSK%28P%29%202017%2034%20T.pdf |
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