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Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts

Haruan (Channa striatus) fillet and mucus extracts have been proven to exhibit a dosedependent antinociceptive activity and enhanced morphine effect. This current study is to establish some of the physical and chemical properties of the bioactive components responsible for haruan antinociceptive act...

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Main Author: Zakaria, Zainul Amiruddin
Format: Thesis
Language:English
Published: 2001
Online Access:http://ethesis.upm.edu.my/id/eprint/3578/1/FPSK_%28M%29_2001_3_F.pdf
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id oai:ethesis.upm.edu.my:3578
record_format eprints
spelling oai:ethesis.upm.edu.my:3578 http://ethesis.upm.edu.my/id/eprint/3578/ Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts Zakaria, Zainul Amiruddin Haruan (Channa striatus) fillet and mucus extracts have been proven to exhibit a dosedependent antinociceptive activity and enhanced morphine effect. This current study is to establish some of the physical and chemical properties of the bioactive components responsible for haruan antinociceptive activity. Five types of solvents (water, methanol, ethanol, chloroform and chloroform:methanol) were used to extract the respective components from freeze-dried haruan fillet. Various salts (NaCI, K Cl, CaCh, MgCh and their combinations (MS))were used to study the involvement of ionic components in mediating the antinociceptive activity of haruan extract. The aqueous portion obtained after a chloroform:methanol extraction of fresh haruan fillet was filtered using three types of Millipore filters (30,000, 10,000 and 5,000 Nominal Molecular Weight Limit (NMWL), respectively. Lastly, the aqueous portion, filtered using the 5,000 NMWL Millipore filters, was purified using the High performance liquid chromatography (HPLC) procedure. 2001-01 Thesis NonPeerReviewed application/pdf en http://ethesis.upm.edu.my/id/eprint/3578/1/FPSK_%28M%29_2001_3_F.pdf Zakaria, Zainul Amiruddin (2001) Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts. Masters thesis, Universiti Putra Malaysia. (FPSK (M) 2001 3).
institution UPM eTHESES
collection UPM eTHESES
language English
description Haruan (Channa striatus) fillet and mucus extracts have been proven to exhibit a dosedependent antinociceptive activity and enhanced morphine effect. This current study is to establish some of the physical and chemical properties of the bioactive components responsible for haruan antinociceptive activity. Five types of solvents (water, methanol, ethanol, chloroform and chloroform:methanol) were used to extract the respective components from freeze-dried haruan fillet. Various salts (NaCI, K Cl, CaCh, MgCh and their combinations (MS))were used to study the involvement of ionic components in mediating the antinociceptive activity of haruan extract. The aqueous portion obtained after a chloroform:methanol extraction of fresh haruan fillet was filtered using three types of Millipore filters (30,000, 10,000 and 5,000 Nominal Molecular Weight Limit (NMWL), respectively. Lastly, the aqueous portion, filtered using the 5,000 NMWL Millipore filters, was purified using the High performance liquid chromatography (HPLC) procedure.
format Thesis
author Zakaria, Zainul Amiruddin
spellingShingle Zakaria, Zainul Amiruddin
Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts
author_facet Zakaria, Zainul Amiruddin
author_sort Zakaria, Zainul Amiruddin
title Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts
title_short Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts
title_full Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts
title_fullStr Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts
title_full_unstemmed Some Physical And Chemical Properties Of The Bioactive Components Responsible For Antinociceptive Activity Of Haruan (Channa striatus) Extracts
title_sort some physical and chemical properties of the bioactive components responsible for antinociceptive activity of haruan (channa striatus) extracts
publishDate 2001
url http://ethesis.upm.edu.my/id/eprint/3578/1/FPSK_%28M%29_2001_3_F.pdf
_version_ 1819310386154831872
score 13.4562235

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