Staff View: Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)

Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)

In the present study, cell mediated immune response in the mammary gland tumour-bearing bitches was studied by evaluating functional capacity of sensitised lymphocytes using Leucocyte Migration Inhibition Test (LMIT). Cell membrane antigens (allogenic type) of different molecular weights separated f...

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Main Authors:	Lonkar, P. S., Adak, A.
Format:	Journal Contribution
Language:	English
Published:	2021
Subjects:	Mammary glands Animal tumours Inhibition Immune response Immunity Migration Dogs Lymphocytes Bitches Antigens Autochthonous varieties Carcinoma Cell membranes
Online Access:	http://agris.upm.edu.my:8080/dspace/handle/0/19231
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spelling	oai:http:--agris.upm.edu.my:0-19231Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)Lonkar, P. S.Adak, A.Mammary glandsAnimal tumoursInhibitionImmune responseImmunityMigrationMammary glandsDogsLymphocytesBitchesAntigensAutochthonous varietiesAntigensCarcinomaCell membranesAnimal tumoursIn the present study, cell mediated immune response in the mammary gland tumour-bearing bitches was studied by evaluating functional capacity of sensitised lymphocytes using Leucocyte Migration Inhibition Test (LMIT). Cell membrane antigens (allogenic type) of different molecular weights separated from mammary gland tumour tissue were subjected to LMIT against leucocytes separated from twenty tumour-bearing bitches and six apparently healthy dogs used as control group. Statistically, the tumour bearing dogs had significantly lower migration index values in comparison to healthy control dogs. Thus, leucocytes separated fom tumour-bearing animals showed positive LMIT response while there was normal migration in the healthy control dogs. It is seen that the functional capacity of T Lymphocytes in the mammary gland tumour-bearing bitches played a major role in cellular immunity and was not affected as indicated by migration inhibition index.2021-08-16T04:07:29Z2021-08-16T04:07:29Z2009Journal ContributionArticleNon-RefereedJurnal Veterinar Malaysia (Malaysia), 21 (2), p. 17-209128-2506http://agris.upm.edu.my:8080/dspace/handle/0/19231MY2021051041enhttps://www.mavma.org.my/2009-volume-21-issue-no-2-dechttp://www.oceandocs.org/license
institution	AGRIS
collection	AGRIS
language	English
topic	Mammary glands Animal tumours Inhibition Immune response Immunity Migration Mammary glands Dogs Lymphocytes Bitches Antigens Autochthonous varieties Antigens Carcinoma Cell membranes Animal tumours
spellingShingle	Mammary glands Animal tumours Inhibition Immune response Immunity Migration Mammary glands Dogs Lymphocytes Bitches Antigens Autochthonous varieties Antigens Carcinoma Cell membranes Animal tumours Lonkar, P. S. Adak, A. Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)
description	In the present study, cell mediated immune response in the mammary gland tumour-bearing bitches was studied by evaluating functional capacity of sensitised lymphocytes using Leucocyte Migration Inhibition Test (LMIT). Cell membrane antigens (allogenic type) of different molecular weights separated from mammary gland tumour tissue were subjected to LMIT against leucocytes separated from twenty tumour-bearing bitches and six apparently healthy dogs used as control group. Statistically, the tumour bearing dogs had significantly lower migration index values in comparison to healthy control dogs. Thus, leucocytes separated fom tumour-bearing animals showed positive LMIT response while there was normal migration in the healthy control dogs. It is seen that the functional capacity of T Lymphocytes in the mammary gland tumour-bearing bitches played a major role in cellular immunity and was not affected as indicated by migration inhibition index.
format	Journal Contribution
author	Lonkar, P. S. Adak, A.
author_facet	Lonkar, P. S. Adak, A.
author_sort	Lonkar, P. S.
title	Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)
title_short	Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)
title_full	Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)
title_fullStr	Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)
title_full_unstemmed	Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)
title_sort	assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (lmit)
publishDate	2021
url	http://agris.upm.edu.my:8080/dspace/handle/0/19231
_version_	1819285535111249920
score	13.4562235

Assessment of cell mediated immune response in spontaneously occurring canine mammary gland tumours by leucocytemiggration inhibition test (LMIT)

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