Process development with bifunctional chiral epoxides to acess single enantiomers of pharmaceutical intermediates
Two selected case studies on process development will be discussed: one is on the enantiocontrolled synthesis of (S)-3-hydroxytetradecanoic acid (2), an intermediate of ONO-4007 (3) possessing anti tumor activity, which employs terminally differentiated double homologation on (S)-epichlorohydrin (EC...
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| Main Authors: | , |
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| 格式: | Proceedings Paper |
| 语言: | English |
| 出版: |
Malaysian Palm oil Board
2015
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| 主题: | |
| 在线阅读: | http://agris.upm.edu.my:8080/dspace/handle/0/8328 |
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