Amphotericin B resistance in Leishmania mexicana: alterations to sterol metabolism and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed that, in each resistant...

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Main Authors: Alpizar-Sosa, Edubiel A., Ithnin, Nur Raihana, Wenbin, Wei, Pountain, Andrew W., Weidt, Stefan K., Donachie, Anne M., Ritchie, Ryan, Dickie, Emily A., Burchmore, Richard J. S., Denny, Paul W., Barrett, Michael P.
Formáid: Article
Foilsithe: Public Library of Science 2022
Clibeanna: Cuir Clib Leis
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