Amphotericin B resistance in Leishmania mexicana: alterations to sterol metabolism and oxidative stress response
Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed that, in each resistant...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
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Public Library of Science
2022
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