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The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position

The multihole collimator is the most commonly used collimator in conventional SPECT cameras for general purpose imaging. However, there are some limitations with this collimator, which includes the lack of sensitivity as a trade-off for obtaining better spatial resolution. This paper looks at the pe...

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Main Authors: Roslan, R. E., Mohd Saad, Wira Hidayat, Saripan, M. Iqbal, Hashim, Sharifah, Choong, W. S.
Format: Article
Language:English
English
Published: 2010
Online Access:http://psasir.upm.edu.my/id/eprint/11644/1/The%20performance%20of%20a%20wire%20mesh%20collimator%20SPECT%20camera%20for%20different%20breast%20volumes%20in%20prone%20position.pdf
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spelling oai:psasir.upm.edu.my:11644 http://psasir.upm.edu.my/id/eprint/11644/ The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position Roslan, R. E. Mohd Saad, Wira Hidayat Saripan, M. Iqbal Hashim, Sharifah Choong, W. S. The multihole collimator is the most commonly used collimator in conventional SPECT cameras for general purpose imaging. However, there are some limitations with this collimator, which includes the lack of sensitivity as a trade-off for obtaining better spatial resolution. This paper looks at the performance of a wire mesh collimator that was introduced recently in order to improve the ability of SPECT cameras in mapping breast cancer cells, utilizing the Technetium-99 m 140 keV radiotracer. In this work, various volumes of breast are modelled and simulated using Monte Carlo N-Particle (MCNP5) code, derived based on the real cup sizes and volumes in prone position. The size of tumour is 1 cm in diameter with tumour to background ratios (TBRs) ranging between TBR from 1:1 to TBR 20:1, and located 2 cm inside breast skin. The results show that wire mesh collimator 1 (WM-1) has the highest sensitivity and signal to noise ratio (SNR) in comparison with wire mesh collimator 2 (WM-2) and the multihole collimator (MHC). This indicates the potential of using a wire mesh collimator for early mapping of breast cancer cells. 2010-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/11644/1/The%20performance%20of%20a%20wire%20mesh%20collimator%20SPECT%20camera%20for%20different%20breast%20volumes%20in%20prone%20position.pdf Roslan, R. E. and Mohd Saad, Wira Hidayat and Saripan, M. Iqbal and Hashim, Sharifah and Choong, W. S. (2010) The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 619 (1-3). pp. 385-387. ISSN 0168-9002 10.1016/j.nima.2009.11.005 English
institution UPM IR
collection UPM IR
language English
English
description The multihole collimator is the most commonly used collimator in conventional SPECT cameras for general purpose imaging. However, there are some limitations with this collimator, which includes the lack of sensitivity as a trade-off for obtaining better spatial resolution. This paper looks at the performance of a wire mesh collimator that was introduced recently in order to improve the ability of SPECT cameras in mapping breast cancer cells, utilizing the Technetium-99 m 140 keV radiotracer. In this work, various volumes of breast are modelled and simulated using Monte Carlo N-Particle (MCNP5) code, derived based on the real cup sizes and volumes in prone position. The size of tumour is 1 cm in diameter with tumour to background ratios (TBRs) ranging between TBR from 1:1 to TBR 20:1, and located 2 cm inside breast skin. The results show that wire mesh collimator 1 (WM-1) has the highest sensitivity and signal to noise ratio (SNR) in comparison with wire mesh collimator 2 (WM-2) and the multihole collimator (MHC). This indicates the potential of using a wire mesh collimator for early mapping of breast cancer cells.
format Article
author Roslan, R. E.
Mohd Saad, Wira Hidayat
Saripan, M. Iqbal
Hashim, Sharifah
Choong, W. S.
spellingShingle Roslan, R. E.
Mohd Saad, Wira Hidayat
Saripan, M. Iqbal
Hashim, Sharifah
Choong, W. S.
The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position
author_facet Roslan, R. E.
Mohd Saad, Wira Hidayat
Saripan, M. Iqbal
Hashim, Sharifah
Choong, W. S.
author_sort Roslan, R. E.
title The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position
title_short The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position
title_full The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position
title_fullStr The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position
title_full_unstemmed The performance of a wire mesh collimator SPECT camera for different breast volumes in prone position
title_sort performance of a wire mesh collimator spect camera for different breast volumes in prone position
publishDate 2010
url http://psasir.upm.edu.my/id/eprint/11644/1/The%20performance%20of%20a%20wire%20mesh%20collimator%20SPECT%20camera%20for%20different%20breast%20volumes%20in%20prone%20position.pdf
_version_ 1782718299279196160
score 12.935284

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