Downregulation of RhoGDIα increased migration and invasion of ER+ MCF7 and ER− MDA-MB-231 breast cancer cells.
Rho GDp dissociation inhibitors (RhoGDIs) can inhibit cell motility, invasion, and metastasis in cancer by inactivating the RhoGTpases. A member of RhoGDI family has been consistently shown to interact with estrogen receptor (eR), and change its transcriptional activity. eR is a receptor known t...
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| Главные авторы: | , , , , , |
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| Формат: | Статья |
| Язык: | English English |
| Опубликовано: |
Landes Bioscience
2013
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| Online-ссылка: | http://psasir.upm.edu.my/id/eprint/28133/1/Downregulation%20of%20RhoGDI%CE%B1%20increased%20migration%20and%20invasion%20of%20ER.pdf |
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