Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus

Providing effective medical care for older patients with type 2 diabetes mellitus (T2D) that may contribute to their active aging has always been challenging. We examined the independent effect of age ≥ 60 years on disease control and its relationship with diabetes-related complications in patients...

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Main Authors: Chew, Boon How, Shariff Ghazali, Sazlina, Ismail, Mastura, Haniff, Jamaiyah, Bujang, Mohd Adam
Format: Article
Language:English
Published: Elsevier 2013
Online Access:http://psasir.upm.edu.my/id/eprint/29566/1/Age%20%E2%89%A5%2060%20years%20was%20an%20independent%20risk%20factor%20for%20diabetes-related%20complications%20despite%20good%20control%20of%20cardiovascular%20risk%20factors%20in%20patients%20with%20type%202%20diabetes%20mellitus.pdf
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spelling oai:psasir.upm.edu.my:29566 http://psasir.upm.edu.my/id/eprint/29566/ Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus Chew, Boon How Shariff Ghazali, Sazlina Ismail, Mastura Haniff, Jamaiyah Bujang, Mohd Adam Providing effective medical care for older patients with type 2 diabetes mellitus (T2D) that may contribute to their active aging has always been challenging. We examined the independent effect of age ≥ 60 years on disease control and its relationship with diabetes-related complications in patients with T2D in Malaysia. This was a cross-sectional study using secondary data from the electronic diabetes registry database Adult Diabetes Control and Management (ADCM). A total of 303 centers participated and contributed a total of 70,889 patients from May 2008 to the end of 2009. Demographic data, details on diabetes, hypertension, dyslipidemia and their treatment modalities, various risk factors and complications were updated annually. Independent associated risk factors were identified using multivariate regression analyses. Fifty-nine percent were female. Malay comprised 61.9%, Chinese 19% and Indian 18%. There were more Chinese, men, longer duration of diabetes and subjects that were leaner or had lower BMI in the older age group. Patients aged ≥ 60 years achieved glycemic and lipid targets but not the desired blood pressure. After adjusting for duration of diabetes, gender, ethnicity, body mass index, disease control and treatment, a significantly higher proportion of patients ≥ 60 years suffered from reported diabetes-related complications. Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors. Our findings caution against the currently recommended control of targets in older T2D patients with more longstanding diseases and complications. Elsevier 2013-05 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29566/1/Age%20%E2%89%A5%2060%20years%20was%20an%20independent%20risk%20factor%20for%20diabetes-related%20complications%20despite%20good%20control%20of%20cardiovascular%20risk%20factors%20in%20patients%20with%20type%202%20diabetes%20mellitus.pdf Chew, Boon How and Shariff Ghazali, Sazlina and Ismail, Mastura and Haniff, Jamaiyah and Bujang, Mohd Adam (2013) Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus. Experimental Gerontology, 48 (5). pp. 485-491. ISSN 0531-5565; ESSN: 1873-6815 10.1016/j.exger.2013.02.017
institution UPM IR
collection UPM IR
language English
description Providing effective medical care for older patients with type 2 diabetes mellitus (T2D) that may contribute to their active aging has always been challenging. We examined the independent effect of age ≥ 60 years on disease control and its relationship with diabetes-related complications in patients with T2D in Malaysia. This was a cross-sectional study using secondary data from the electronic diabetes registry database Adult Diabetes Control and Management (ADCM). A total of 303 centers participated and contributed a total of 70,889 patients from May 2008 to the end of 2009. Demographic data, details on diabetes, hypertension, dyslipidemia and their treatment modalities, various risk factors and complications were updated annually. Independent associated risk factors were identified using multivariate regression analyses. Fifty-nine percent were female. Malay comprised 61.9%, Chinese 19% and Indian 18%. There were more Chinese, men, longer duration of diabetes and subjects that were leaner or had lower BMI in the older age group. Patients aged ≥ 60 years achieved glycemic and lipid targets but not the desired blood pressure. After adjusting for duration of diabetes, gender, ethnicity, body mass index, disease control and treatment, a significantly higher proportion of patients ≥ 60 years suffered from reported diabetes-related complications. Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors. Our findings caution against the currently recommended control of targets in older T2D patients with more longstanding diseases and complications.
format Article
author Chew, Boon How
Shariff Ghazali, Sazlina
Ismail, Mastura
Haniff, Jamaiyah
Bujang, Mohd Adam
spellingShingle Chew, Boon How
Shariff Ghazali, Sazlina
Ismail, Mastura
Haniff, Jamaiyah
Bujang, Mohd Adam
Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
author_facet Chew, Boon How
Shariff Ghazali, Sazlina
Ismail, Mastura
Haniff, Jamaiyah
Bujang, Mohd Adam
author_sort Chew, Boon How
title Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
title_short Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
title_full Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
title_fullStr Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
title_full_unstemmed Age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
title_sort age ≥ 60 years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
publisher Elsevier
publishDate 2013
url http://psasir.upm.edu.my/id/eprint/29566/1/Age%20%E2%89%A5%2060%20years%20was%20an%20independent%20risk%20factor%20for%20diabetes-related%20complications%20despite%20good%20control%20of%20cardiovascular%20risk%20factors%20in%20patients%20with%20type%202%20diabetes%20mellitus.pdf
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