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5-Fluorouracil induce the expression of TLR4 on HCT116 colorectal cancer cell line expressing different variants of TLR4

Two common single nucleotide polymorphisms (SNPs) of the human TLR4 gene, namely Asp299Gly (D299G) and Thr399Ile (T399I), have been shown to impair the ability of certain individuals to respond properly to TLR4 ligands. 5-Fluorouracil (5-FU) is widely used for the treatment of patients with advanced...

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Библиографические подробности
Главные авторы:	Davoodi, Homa, Hashemi, Seyed Reza, Seow, Heng Fong
Формат:	Статья
Язык:	English
Опубликовано:	School of Pharmacy, Shaheed Beheshti Medical University 2013
Online-ссылка:	http://psasir.upm.edu.my/id/eprint/29593/1/5.pdf
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