Synthesis and SAR study of diarylpentanoid analogues as new anti-inflammatory agents

A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferone gamma (IFN-γ)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Twelve compounds (9, 25, 28, 43, 63, 64, 81, 83, 84, 86, 88...

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Huvudupphovsmän: Leong, Sze Wei, Mohd Faudzi, Siti Munirah, Abas, Faridah, Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Lam, Kok Wai, Abdul Bahari, Mohd Nazri, Ahmad, Syahida, Tham, Chau Ling, Shaari, Khozirah, Lajis, Md. Nordin
Materialtyp: Artikel
Språk:English
Publicerad: MDPI 2014
Länkar:http://psasir.upm.edu.my/id/eprint/35571/1/Synthesis%20and%20Sar%20Study%20of%20Diarylpentanoid%20Analogues%20as%20New.pdf
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