封面图片

Synthesis and SAR study of diarylpentanoid analogues as new anti-inflammatory agents

A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferone gamma (IFN-γ)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Twelve compounds (9, 25, 28, 43, 63, 64, 81, 83, 84, 86, 88...

Saved in:

书目详细资料
Main Authors:	Leong, Sze Wei, Mohd Faudzi, Siti Munirah, Abas, Faridah, Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Lam, Kok Wai, Abdul Bahari, Mohd Nazri, Ahmad, Syahida, Tham, Chau Ling, Shaari, Khozirah, Lajis, Md. Nordin
格式:	Article
语言:	English
出版:	MDPI 2014
在线阅读:	http://psasir.upm.edu.my/id/eprint/35571/1/Synthesis%20and%20Sar%20Study%20of%20Diarylpentanoid%20Analogues%20as%20New.pdf
标签:	添加标签没有标签, 成为第一个标记此记录!

相似书籍

Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxide inhibitors
由: Mohd Faudzi, S. M., et al.
出版: (2015)

Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities
由: Ka-Heng, Lee, et al.
出版: (2009)

Molecular pathways modulated by curcumin analogue, diarylpentanoids in cancer
由: Paulraj, Felicia Simone, et al.
出版: (2019)

Design, synthesis, anti-inflammatory activity evaluation, and structure-activities relationship (SAR) study of diarylpentanoid derivatives
由: Leong, Sze Wei
出版: (2014)

Design, synthesis, anti-inflammatory activity evaluation, and structure-activities relationship (SAR) study of diarylpentanoid derivatives
由: Leong, Sze Wei
出版: (2014)

Design, synthesis, anti-inflammatory activity evaluation, and structure-activities relationship (SAR) study of diarylpentanoid derivatives /
由: Leong, Sze Wei.
出版: (2014)

Development and structure activity relationship of diarylpentadienone and chalcone analogues as potential anti-inflammatory agent
由: Mohd Faudzi, Siti Munirah
出版: (2015)

Development and structure activity relationship of diarylpentadienone and chalcone analogues as potential anti-inflammatory agent
由: Mohd Faudzi, Siti Munirah
出版: (2015)

Development and structure activity relationship of diarylpentadienone and chalcone analogues as potential anti-inflammatory agent /
由: Siti Munirah Mohd Faudzi
出版: (2015)

Effect of diarylpentanoid analogues on lipopolysaccharide-induced interleukin-6 and interleukin-8 gene expression in airway inflammation
由: Liew, Kong Yen, et al.
出版: (2019)

Involvement of the cholinergic and dopaminergic systems in antinociceptive activities of diarylpentanoid analogues in mice /
由: Celestina Hendrikus.
出版: (2017)

Effect of diarylpentanoid analogues of curcumin on a canine prostate carcinoma cell line /
由: Wanxin,Chrisann Po.
出版: (2019)

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines
由: Mohd Aluwi, Mohd Fadhlizil Fasihi, et al.
出版: (2016)

In vitro and in silico evaluations of diarylpentanoid series as a-glucosidase inhibitor
由: Leong, Sze Wei, et al.
出版: (2018)

The mutagenic study of benzimidazole analogues: Structure activity relationship (SAR) /
由: Siti Soleha Abdullah.
出版: (2018)

Anti-inflammatory activities of curcumin-like diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4- hydroxybenzylidene)cyclohexen-1-ol in mice /
由: Norhidayah Badrul Hisham.
出版: (2017)

Protective effect of benzimidazole analogues against hydrogen peroxide (H₂O₂) toxicity in normal mouse fibroblast (3T3) cell line; structure-activity relationships (SAR) /
由: Fatin Amira Mohd Nazri.
出版: (2018)

Investigation on the effect of diarylpentanoid analogues on lipopolysacharides-induced IL-6 and IL-8 gene expression in airway inflammation /
由: Nur A'dilah Rosly.

Imaging in SARS /
出版: (2004)

Molecular target of synthetic curcuminoid analogue 2,6- bis-(4-hydroxy-3-methoxy-benzylidene)-cyclohexanone in inflammation /
由: Tham, Chau Ling.

Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: synthesis, biological activity, crystal structure, and in silico evaluation
由: Rullah, Kamal, et al.
出版: (2014)

Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol, and its possible mechanisms of action in mice
由: Ong, Hui Ming, et al.
出版: (2021)

SARS : a case study in emerging infections /
出版: (2005)

SARS : how a global epidemic was stopped.
出版: (2006)

SARS : reception and interpretation in three Chinese cities /
出版: (2007)

Oestrogenic activity of mimosine on MCF-7 breast cancer cell line through the ERα-mediated pathway
由: Huq, Akm Moyeenul, et al.
出版: (2019)

The involvement of L-arginine-nitric ox-ide-cGMP-ATP-sensitive K+ channel pathway in antinocicep-tion of BBHC, a novel diarylpentanoid analogue, in mice model
由: Hui, Ming Ong, et al.
出版: (2021)

Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies
由: Mohd Faudzi, Siti Munirah, et al.
出版: (2020)

Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro pLDH and in vivo zebrafish toxicity assessment
由: Ramli, Amirah Hani, et al.
出版: (2024)

Chemopreventive effects of a curcumin‐like diarylpentanoid [2,6‐bis(2,5‐dimethoxybenzylidene)cyclohexanone] in cellular targets of rheumatoid arthritis in vitro
由: Lee, Ka Heng, et al.
出版: (2015)

Method of treating inflammatory disease with cardamonin
由: Israf Ali, Daud Ahmad, et al.
出版: (2011)

SARS- and Other Coronaviruses Laboratory Protocols /
出版: (2008)

SARS- and other coronaviruses : laboratory protocols /
出版: (2008)

An eco-friendly and new facile method for synthesis of prenylated or geranylated acylphloroglucinol-based xanthenones
由: Tamil Segaran, Raaginie, et al.
出版: (2024)

In-vitro and in-silico evaluations of heterocyclic-containing diarylpentanoids as Bcl-2 inhibitors against LoVo colorectal cancer cells
由: Leong, Sze Wei, et al.
出版: (2020)

Molecular Biology of the SARS-Coronavirus
出版: (2010)

Geocoding of spaceborne SAR imagery
由: Kwoh, L. K.
出版: (2015)

Identification of curcumin analogues with anti-seizure potential in vivo using chemical and genetic zebrafish larva seizure models
由: Choo, Brandon Kar Meng, et al.
出版: (2021)

Design of 8-bit SAR-ADC CMOS
由: Hassan, Hur A., et al.
出版: (2009)

Models and analogues in biology /
出版: (1960)