The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation
The use of different dependent doses design offers unique opportunities to advance the study of diseases through the investigation of their respective outcomes at multi-disciplinary level. Such design can increase our understanding of the factors that shape disease establishment, course development...
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KPK Publishers
2014
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oai:psasir.upm.edu.my:35815 http://psasir.upm.edu.my/id/eprint/35815/ The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation Osman, Abdinasir Yusuf Abdullah, Faez Firdaus Jesse Adamu, Lawan Abdullah, Tuba Thabitah Azuan, Mohd Hero Omar, Abdul Rahman Haron, Abdul Wahid Saharee, Abdul Aziz The use of different dependent doses design offers unique opportunities to advance the study of diseases through the investigation of their respective outcomes at multi-disciplinary level. Such design can increase our understanding of the factors that shape disease establishment, course development and distribution of lesions in space and time. This paper utilizes three different doses of C. pseudotuberculosis, 103, 105 and 107 colony forming unit (CFU/ml) and illustrates their potential of disease induction at a range of histo-pathological and molecular scales. A mouse model is used to demonstrate the potential aspects of the doses in relation to the outcome of interest. Our approach is based on comparing the observed patterns of clinical features, postmortem and gross finding, as well as histo-pathological and molecular levels. KPK Publishers 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/35815/1/The%20study%20of%20caseous%20lymphadenitis%20dose%20dependent%20infection%20of%20C.%20pseudotuberculosis%20in%20mouse%20model%20via%20oral%20inoculation.pdf Osman, Abdinasir Yusuf and Abdullah, Faez Firdaus Jesse and Adamu, Lawan and Abdullah, Tuba Thabitah and Azuan, Mohd Hero and Omar, Abdul Rahman and Haron, Abdul Wahid and Saharee, Abdul Aziz (2014) The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation. Research Opinions in Animal & Veterinary Sciences, 4 (3). pp. 163-169. ISSN 2221-1896; ESSN: 2223-0343 http://www.roavs.com/Abstract/Issue-3-2014/163-169.htm |
| institution |
UPM IR |
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UPM IR |
| language |
English |
| description |
The use of different dependent doses design offers unique opportunities to advance the study of diseases through the investigation of their respective outcomes at multi-disciplinary level. Such design can increase our understanding of the factors that shape disease establishment, course development and distribution of lesions in space and time. This paper utilizes three different doses of C. pseudotuberculosis, 103, 105 and 107 colony forming unit (CFU/ml) and illustrates their potential of disease induction at a range of histo-pathological and molecular scales. A mouse model is used to demonstrate the potential aspects of the doses in relation to the outcome of interest. Our approach is based on comparing the observed patterns of clinical features, postmortem and gross finding, as well as histo-pathological and molecular levels. |
| format |
Article |
| author |
Osman, Abdinasir Yusuf Abdullah, Faez Firdaus Jesse Adamu, Lawan Abdullah, Tuba Thabitah Azuan, Mohd Hero Omar, Abdul Rahman Haron, Abdul Wahid Saharee, Abdul Aziz |
| spellingShingle |
Osman, Abdinasir Yusuf Abdullah, Faez Firdaus Jesse Adamu, Lawan Abdullah, Tuba Thabitah Azuan, Mohd Hero Omar, Abdul Rahman Haron, Abdul Wahid Saharee, Abdul Aziz The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation |
| author_facet |
Osman, Abdinasir Yusuf Abdullah, Faez Firdaus Jesse Adamu, Lawan Abdullah, Tuba Thabitah Azuan, Mohd Hero Omar, Abdul Rahman Haron, Abdul Wahid Saharee, Abdul Aziz |
| author_sort |
Osman, Abdinasir Yusuf |
| title |
The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation |
| title_short |
The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation |
| title_full |
The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation |
| title_fullStr |
The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation |
| title_full_unstemmed |
The study of caseous lymphadenitis: dose dependent infection of C. pseudotuberculosis in mouse model via oral inoculation |
| title_sort |
study of caseous lymphadenitis: dose dependent infection of c. pseudotuberculosis in mouse model via oral inoculation |
| publisher |
KPK Publishers |
| publishDate |
2014 |
| url |
http://psasir.upm.edu.my/id/eprint/35815/1/The%20study%20of%20caseous%20lymphadenitis%20dose%20dependent%20infection%20of%20C.%20pseudotuberculosis%20in%20mouse%20model%20via%20oral%20inoculation.pdf |
| _version_ |
1819295823705407488 |
| score |
13.4562235 |