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Chemical characterization and antioxidant activity of three medicinal Apiaceae species

Centella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredients in pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and electrospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differe...

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Autors principals: Maulidiani,, Abas, Faridah, Khatib, Alfi, Shaari, Khozirah, Lajis, Md Nordin
Format: Article
Idioma:English
Publicat: Elsevier 2014
Accés en línia:http://psasir.upm.edu.my/id/eprint/36771/1/Chemical%20characterization%20and%20antioxidant%20activity%20of%20three%20medicinal%20Apiaceae%20species.pdf
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spelling oai:psasir.upm.edu.my:36771 http://psasir.upm.edu.my/id/eprint/36771/ Chemical characterization and antioxidant activity of three medicinal Apiaceae species Maulidiani, Abas, Faridah Khatib, Alfi Shaari, Khozirah Lajis, Md Nordin Centella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredients in pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and electrospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three different Pegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabolite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-type triterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotyle species consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due to the difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evaluated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, and xanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potent antioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 μg/ml; XOI = 87.68 μg/ml) as compared to H. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 μg/ml; XOI = 32.23 μg/ml) and H. sibthorpioides (TPC = 56.23 mg/100 g DW; DPPH = 37.86 μg/ml; XOI = 14.73. μg/ml). Elsevier 2014-04 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36771/1/Chemical%20characterization%20and%20antioxidant%20activity%20of%20three%20medicinal%20Apiaceae%20species.pdf Maulidiani, and Abas, Faridah and Khatib, Alfi and Shaari, Khozirah and Lajis, Md Nordin (2014) Chemical characterization and antioxidant activity of three medicinal Apiaceae species. Industrial Crops and Products, 55. pp. 238-247. ISSN 0926-6690; ESSN: 1872-633X 10.1016/j.indcrop.2014.02.013
institution UPM IR
collection UPM IR
language English
description Centella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredients in pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and electrospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three different Pegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabolite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-type triterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotyle species consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due to the difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evaluated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, and xanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potent antioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 μg/ml; XOI = 87.68 μg/ml) as compared to H. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 μg/ml; XOI = 32.23 μg/ml) and H. sibthorpioides (TPC = 56.23 mg/100 g DW; DPPH = 37.86 μg/ml; XOI = 14.73. μg/ml).
format Article
author Maulidiani,
Abas, Faridah
Khatib, Alfi
Shaari, Khozirah
Lajis, Md Nordin
spellingShingle Maulidiani,
Abas, Faridah
Khatib, Alfi
Shaari, Khozirah
Lajis, Md Nordin
Chemical characterization and antioxidant activity of three medicinal Apiaceae species
author_facet Maulidiani,
Abas, Faridah
Khatib, Alfi
Shaari, Khozirah
Lajis, Md Nordin
author_sort Maulidiani,
title Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_short Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_full Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_fullStr Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_full_unstemmed Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_sort chemical characterization and antioxidant activity of three medicinal apiaceae species
publisher Elsevier
publishDate 2014
url http://psasir.upm.edu.my/id/eprint/36771/1/Chemical%20characterization%20and%20antioxidant%20activity%20of%20three%20medicinal%20Apiaceae%20species.pdf
_version_ 1819295915648745472
score 13.4562235

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