In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog

Limited tumor penetrability of anti-cancer drugs is recognized as one of the major factors that lead to poor anti-tumor activity. SRJ09 (3,19-(2-bromobenzylidene) andrographolide) has been identified as a lead anti-cancer agent for colon cancer. Recently, this compound was shown by us to be a mutant...

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Bibliographic Details
Main Authors: Wong, Charng Choon, Periasamy, Nagarajan, Sagineedu, Sreenivasa Rao, Mohd Sidik, Shiran, Sumon, Md. Shariful Hasan, Loadman, Paul, Phillips, Roger, Lajis, Md. Nordin, Stanslas, Johnson
Format: Article
Language:English
Published: Springer 2014
Online Access:http://psasir.upm.edu.my/id/eprint/37996/1/In%20vitro%203D%20colon%20tumor%20penetrability%20of%20SRJ09%2C%20a%20new%20anti-cancer%20andrographolide%20analog.pdf