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Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs

The purpose of this study was to investigate the effect of vaccination against infectious bursal disease (IBD) via topical application of IBD vaccine (MyVAC UPM93) either with or without liposomes as vaccine carrier in 18-day-old specific pathogen free (SPF) embryonated chicken eggs. The study demon...

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Päätekijät: W., Mukminah Sakinah, Bejo, Mohd Hair, Abdul Rahman, Omar, Ideris, Aini
Aineistotyyppi: Conference or Workshop Item
Kieli:English
Julkaistu: Faculty of Veterinary Medicine, Universiti Putra Malaysia 2013
Linkit:http://psasir.upm.edu.my/id/eprint/41225/1/41225.pdf
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id oai:psasir.upm.edu.my:41225
record_format eprints
spelling oai:psasir.upm.edu.my:41225 http://psasir.upm.edu.my/id/eprint/41225/ Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs W., Mukminah Sakinah Bejo, Mohd Hair Abdul Rahman, Omar Ideris, Aini The purpose of this study was to investigate the effect of vaccination against infectious bursal disease (IBD) via topical application of IBD vaccine (MyVAC UPM93) either with or without liposomes as vaccine carrier in 18-day-old specific pathogen free (SPF) embryonated chicken eggs. The study demonstrated that the IBD vaccine group alone could induce high and protective level of IBD antibody titre (2545+1884 ELISA unit) in the chicks at 14 days of age. In contrast, IBD antibody titre was not detected in the liposomes, combination of liposomes with IBD vaccine and control groups of chickens. It appears that further study is needed to improve the liposome as a vaccine carrier to accelerate vaccine delivery to the target organ and enhance antibody titre. It was concluded that topical application of IBD vaccine (MyVAC UPM93) in 18-day-old SPF embryonated chicken eggs can be an effective vaccination route against IBD. Faculty of Veterinary Medicine, Universiti Putra Malaysia 2013 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/41225/1/41225.pdf W., Mukminah Sakinah and Bejo, Mohd Hair and Abdul Rahman, Omar and Ideris, Aini (2013) Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs. In: World’s Poultry Science Association (Malaysia Branch) and World Veterinary Poultry Association (Malaysia Branch) Scientific Conference 2013, 30 Nov.-1 Dec. 2013, Faculty of Veterinary Medicine, Universiti Putra Malaysia. (pp. 85-87). http://www.vet.upm.edu.my/dokumen/90301_proceeding_WPSA_V2_first_second_XX_new_20121013_%281%29.pdf
institution UPM IR
collection UPM IR
language English
description The purpose of this study was to investigate the effect of vaccination against infectious bursal disease (IBD) via topical application of IBD vaccine (MyVAC UPM93) either with or without liposomes as vaccine carrier in 18-day-old specific pathogen free (SPF) embryonated chicken eggs. The study demonstrated that the IBD vaccine group alone could induce high and protective level of IBD antibody titre (2545+1884 ELISA unit) in the chicks at 14 days of age. In contrast, IBD antibody titre was not detected in the liposomes, combination of liposomes with IBD vaccine and control groups of chickens. It appears that further study is needed to improve the liposome as a vaccine carrier to accelerate vaccine delivery to the target organ and enhance antibody titre. It was concluded that topical application of IBD vaccine (MyVAC UPM93) in 18-day-old SPF embryonated chicken eggs can be an effective vaccination route against IBD.
format Conference or Workshop Item
author W., Mukminah Sakinah
Bejo, Mohd Hair
Abdul Rahman, Omar
Ideris, Aini
spellingShingle W., Mukminah Sakinah
Bejo, Mohd Hair
Abdul Rahman, Omar
Ideris, Aini
Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
author_facet W., Mukminah Sakinah
Bejo, Mohd Hair
Abdul Rahman, Omar
Ideris, Aini
author_sort W., Mukminah Sakinah
title Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
title_short Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
title_full Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
title_fullStr Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
title_full_unstemmed Infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
title_sort infectious bursal disease vaccine delivery via topical application in 18-day-old specific pathogen free embryonated chicken eggs
publisher Faculty of Veterinary Medicine, Universiti Putra Malaysia
publishDate 2013
url http://psasir.upm.edu.my/id/eprint/41225/1/41225.pdf
_version_ 1819296339840729088
score 13.4562235

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