Development and validation of high resolution melting assays for high-throughput screening of BDNF rs6265 and DAT1 rs40184
Introduction: One of the commonly used techniques for mutation screening is High Resolution Melting (HRM) analysis. HRM is a post PCR method that relies on the detection of the fluorescent signals acquired due to the release of DNA intercalated dyes upon the melting of dsDNA to ssDNA. The method is...
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia