Factors affecting nucleolytic efficiency of some ternary metal complexes with DNA binding and recognition domains. Crystal and molecular structure of Zn(phen)(edda)
The binding selectivity of the M(phen)(edda) (M = Cu, Co, Ni, Zn; phen = 1,10-phenanthroline, edda = ethylenediaminediacetic acid) complexes towards ds(CG)6, ds(AT)6 and ds(CGCGAATTCGCG) B-form oligonucleotide duplexes were studied by CD spectroscopy and molecular modeling. The binding mode is inter...
Saved in:
Main Authors: | Seng, Hoi Ling, Ong, Alan Han Kiat, Raja Abdul Rahman, Raja Noor Zaliha, Mohd Yamin, Bohari, Tiekink, Edward R. T., Tan, Kong Wai, Maah, Mohd Jamil, Caracelli, Ignez, Ng, Chew Hee |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2008
|
Online Access: | http://psasir.upm.edu.my/id/eprint/7325/1/Factors%20affecting%20nucleolytic%20efficiency%20of%20some%20ternary%20metal%20complexes%20with%20DNA%20binding%20and%20recognition%20domains.%20Crystal%20and%20molecular%20structure%20of%20Zn%28phen%29%28edda%29.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Factors affecting the nucleolytic cleavage of DNA by (N,N′-ethylenendiaminediacetato)metal(II) complexes, M(edda). Crystal structure of Co(edda)
by: Ng, Chew Hee, et al.
Published: (2006) -
Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3 methyl-picolinic acid
by: Seng, Hoi Ling, et al.
Published: (2010) -
Copper(II) complexes of methylated glycine derivatives: effect of methyl substituent on their DNA binding and nucleolytic property
by: Seng, Hoi Ling, et al.
Published: (2009) -
Electrochemical studies of [Cu(phen)(c-mala)] N03, [Cu(phen)2CI2]·5.5H20, [Cu(phen)(edda)·5.5H20, and their interaction with DNA and H202 /
by: Yaw, Chong Wey. -
Electrochemical studies of [Cu(phen)(c-mala)] N03, [Cu(phen)2CI2]·5.5H20, [Cu(phen)(edda)·5.5H20, and their interaction with DNA and H202
by: Yaw, Chong Wey
Published: (2012)