Toxicity and safety evaluation of doxorubicin-loaded cockleshell-derived calcium carbonate nanoparticle in dogs

Doxorubicin (DOX) is a potent anticancer agent with cytotoxic effects which limit its clinical usage. This effect is due to its nonselective nature causing injury to the cells as a result of reactive free oxygen radical's release. Cockleshell-derived calcium carbonate nanoparticle (CS-CaCO3NP)...

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Bibliographic Details
Main Authors: Danmaigoro, Abu Bakar, Selvarajah, Gayathri Thevi, Mohd Noor, Mohd Hezmee, Mahmud, Rozi, Abu Bakar @ Zakaria, Md Zuki
Format: Article
Published: Hindawi 2018
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