Evaluation of a recombinant Newcastle disease virus expressing human IL12 against human breast cancer
The Newcastle disease virus (NDV) strain AF2240 is an avian avulavirus that has been demonstrated to possess oncolytic activity against cancer cells. However, to illicit a greater anti-cancer immune response, it is believed that the incorporation of immunostimulatory genes such as IL12 into a recomb...
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Nature Publishing Group
2019
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