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Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development

The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is...

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Asıl Yazarlar: Chean, Yeah Yong, Hui, Kian Ong, Hooi, Chia Tang, Swee, Keong Yeap, Omar, Abdul Rahman, Kok, Lian Ho, Wen, Siang Tan
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: PeerJ 2019
Online Erişim:http://psasir.upm.edu.my/id/eprint/80249/1/Infectious%20hematopoietic%20necrosis%20virus%20advances%20in%20diagnosis%20and%20vaccine%20development.pdf
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id oai:psasir.upm.edu.my:80249
record_format eprints
spelling oai:psasir.upm.edu.my:80249 http://psasir.upm.edu.my/id/eprint/80249/ Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development Chean, Yeah Yong Hui, Kian Ong Hooi, Chia Tang Swee, Keong Yeap Omar, Abdul Rahman Kok, Lian Ho Wen, Siang Tan The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is no effective treatment for IHNV infected fishes; therefore, early detection and depopulation of the infected fishes remain the most common practices to contain the spread of IHNV. Apart from hygiene practices in aquaculture and isolation of infected fishes, loss of fishes due to IHNV infection can also be significantly reduced through vaccination programs. In the current review, some of the diagnostic methods for IHNV, spanning from clinical diagnosis to cell culture, serological and molecular methods are discussed in detail. In addition, some of the most significant candidate vaccines for IHNV are also extensively discussed, particularly the DNA vaccines. PeerJ 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/80249/1/Infectious%20hematopoietic%20necrosis%20virus%20advances%20in%20diagnosis%20and%20vaccine%20development.pdf Chean, Yeah Yong and Hui, Kian Ong and Hooi, Chia Tang and Swee, Keong Yeap and Omar, Abdul Rahman and Kok, Lian Ho and Wen, Siang Tan (2019) Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development. PeerJ, 7. pp. 1-30. ISSN 2167-8359 https://pubmed.ncbi.nlm.nih.gov/31341728/ 10.7717/peerj.7151
institution UPM IR
collection UPM IR
language English
description The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is no effective treatment for IHNV infected fishes; therefore, early detection and depopulation of the infected fishes remain the most common practices to contain the spread of IHNV. Apart from hygiene practices in aquaculture and isolation of infected fishes, loss of fishes due to IHNV infection can also be significantly reduced through vaccination programs. In the current review, some of the diagnostic methods for IHNV, spanning from clinical diagnosis to cell culture, serological and molecular methods are discussed in detail. In addition, some of the most significant candidate vaccines for IHNV are also extensively discussed, particularly the DNA vaccines.
format Article
author Chean, Yeah Yong
Hui, Kian Ong
Hooi, Chia Tang
Swee, Keong Yeap
Omar, Abdul Rahman
Kok, Lian Ho
Wen, Siang Tan
spellingShingle Chean, Yeah Yong
Hui, Kian Ong
Hooi, Chia Tang
Swee, Keong Yeap
Omar, Abdul Rahman
Kok, Lian Ho
Wen, Siang Tan
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
author_facet Chean, Yeah Yong
Hui, Kian Ong
Hooi, Chia Tang
Swee, Keong Yeap
Omar, Abdul Rahman
Kok, Lian Ho
Wen, Siang Tan
author_sort Chean, Yeah Yong
title Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
title_short Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
title_full Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
title_fullStr Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
title_full_unstemmed Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
title_sort infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
publisher PeerJ
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/80249/1/Infectious%20hematopoietic%20necrosis%20virus%20advances%20in%20diagnosis%20and%20vaccine%20development.pdf
_version_ 1819299659636539392
score 13.4562235

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