Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is...
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
PeerJ
2019
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| الوصول للمادة أونلاين: | http://psasir.upm.edu.my/id/eprint/80249/1/Infectious%20hematopoietic%20necrosis%20virus%20advances%20in%20diagnosis%20and%20vaccine%20development.pdf |
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oai:psasir.upm.edu.my:80249 http://psasir.upm.edu.my/id/eprint/80249/ Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development Chean, Yeah Yong Hui, Kian Ong Hooi, Chia Tang Swee, Keong Yeap Omar, Abdul Rahman Kok, Lian Ho Wen, Siang Tan The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is no effective treatment for IHNV infected fishes; therefore, early detection and depopulation of the infected fishes remain the most common practices to contain the spread of IHNV. Apart from hygiene practices in aquaculture and isolation of infected fishes, loss of fishes due to IHNV infection can also be significantly reduced through vaccination programs. In the current review, some of the diagnostic methods for IHNV, spanning from clinical diagnosis to cell culture, serological and molecular methods are discussed in detail. In addition, some of the most significant candidate vaccines for IHNV are also extensively discussed, particularly the DNA vaccines. PeerJ 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/80249/1/Infectious%20hematopoietic%20necrosis%20virus%20advances%20in%20diagnosis%20and%20vaccine%20development.pdf Chean, Yeah Yong and Hui, Kian Ong and Hooi, Chia Tang and Swee, Keong Yeap and Omar, Abdul Rahman and Kok, Lian Ho and Wen, Siang Tan (2019) Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development. PeerJ, 7. pp. 1-30. ISSN 2167-8359 https://pubmed.ncbi.nlm.nih.gov/31341728/ 10.7717/peerj.7151 |
| institution |
UPM IR |
| collection |
UPM IR |
| language |
English |
| description |
The aquaculture of salmonid fishes is a multi-billion dollar industry with production over 3 million tons annually. However, infectious hematopoietic necrosis virus (IHNV), which infects and kills salmon and trout, significantly reduces the revenue of the salmon farming industry. Currently, there is no effective treatment for IHNV infected fishes; therefore, early detection and depopulation of the infected fishes remain the most common practices to contain the spread of IHNV. Apart from hygiene practices in aquaculture and isolation of infected fishes, loss of fishes due to IHNV infection can also be significantly reduced through vaccination programs. In the current review, some of the diagnostic methods for IHNV, spanning from clinical diagnosis to cell culture, serological and molecular methods are discussed in detail. In addition, some of the most significant candidate vaccines for IHNV are also extensively discussed, particularly the DNA vaccines. |
| format |
Article |
| author |
Chean, Yeah Yong Hui, Kian Ong Hooi, Chia Tang Swee, Keong Yeap Omar, Abdul Rahman Kok, Lian Ho Wen, Siang Tan |
| spellingShingle |
Chean, Yeah Yong Hui, Kian Ong Hooi, Chia Tang Swee, Keong Yeap Omar, Abdul Rahman Kok, Lian Ho Wen, Siang Tan Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| author_facet |
Chean, Yeah Yong Hui, Kian Ong Hooi, Chia Tang Swee, Keong Yeap Omar, Abdul Rahman Kok, Lian Ho Wen, Siang Tan |
| author_sort |
Chean, Yeah Yong |
| title |
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_short |
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_full |
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_fullStr |
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_full_unstemmed |
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| title_sort |
infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development |
| publisher |
PeerJ |
| publishDate |
2019 |
| url |
http://psasir.upm.edu.my/id/eprint/80249/1/Infectious%20hematopoietic%20necrosis%20virus%20advances%20in%20diagnosis%20and%20vaccine%20development.pdf |
| _version_ |
1819299659636539392 |
| score |
13.4562235 |