Cover Image

PET-CT in esophageal cancer management: a cost effectiveness analysis study

The present investigation dealt with the assessment of clinicians perceived views on the impact of PET-CT in esophageal cancer management from practicality, clinical efficacy and cost –effectiveness point of views. Reviews on publication and retrospective data to develop and carry out a decision-ma...

Full description

Saved in:
Bibliographic Details
Main Authors: Azmi, Nor Aniza, Abdul Razak, Hairil Rashmizal, Vinjamuri, Sobhan
Format: Article
Language:English
Published: Universiti Teknologi Malaysia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/81688/1/PET-CT%20in%20esophageal%20cancer.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:psasir.upm.edu.my:81688
record_format eprints
spelling oai:psasir.upm.edu.my:81688 http://psasir.upm.edu.my/id/eprint/81688/ PET-CT in esophageal cancer management: a cost effectiveness analysis study Azmi, Nor Aniza Abdul Razak, Hairil Rashmizal Vinjamuri, Sobhan The present investigation dealt with the assessment of clinicians perceived views on the impact of PET-CT in esophageal cancer management from practicality, clinical efficacy and cost –effectiveness point of views. Reviews on publication and retrospective data to develop and carry out a decision-making model-based economic evaluation to investigate the relative cost-effectiveness of PET/CT in esophageal cancer management staging compared with conventional pathway. Clinicians identified from patient medical records were included in the survey. Retrospective analysis of patient data from 2001-2008 was taken from esophageal cancer patient medical records and North West Cancer Intelligence Services (NWCIS) database. A decision tree was developed using TREEAGE software. The results of the cost-effectiveness analysis were presented in terms of the incremental cost-effectiveness ratios (I-CERs). PET compared with conventional work-up results for ICER for the strategy estimated at £28,460 per QALY; PET/CT compared with PET for ICER was £ 32,590 per QALY; and the ICER for PET/CT combined with conventional work-up versus PET/CT was £ 44,118. The package became more expensive with each additional diagnostic test added to PET and more effective in terms of QALYs gained. The conventional work-up was the preferred options as probabilistic sensitivity analysis showed at a willingness-to-pay threshold of £ 20,000 per QALY. Result of the current analysis suggested that the use of PET/CT in the diagnosis of esophageal cancer was unlikely to be cost-effective given the current willingness-to-pay thresholds that were accepted in the United Kingdom by decision-making bodies such as the National Institute for Health and Clinical Excellence. Universiti Teknologi Malaysia 2019-02-04 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81688/1/PET-CT%20in%20esophageal%20cancer.pdf Azmi, Nor Aniza and Abdul Razak, Hairil Rashmizal and Vinjamuri, Sobhan (2019) PET-CT in esophageal cancer management: a cost effectiveness analysis study. Malaysian Journal of Fundamental and Applied Sciences, 15 (1). pp. 121-124. ISSN 2289-5981; ESSN: 2289-599X https://mjfas.utm.my/index.php/mjfas/article/view/1143 10.11113/mjfas.v15n1.1143
institution UPM IR
collection UPM IR
language English
description The present investigation dealt with the assessment of clinicians perceived views on the impact of PET-CT in esophageal cancer management from practicality, clinical efficacy and cost –effectiveness point of views. Reviews on publication and retrospective data to develop and carry out a decision-making model-based economic evaluation to investigate the relative cost-effectiveness of PET/CT in esophageal cancer management staging compared with conventional pathway. Clinicians identified from patient medical records were included in the survey. Retrospective analysis of patient data from 2001-2008 was taken from esophageal cancer patient medical records and North West Cancer Intelligence Services (NWCIS) database. A decision tree was developed using TREEAGE software. The results of the cost-effectiveness analysis were presented in terms of the incremental cost-effectiveness ratios (I-CERs). PET compared with conventional work-up results for ICER for the strategy estimated at £28,460 per QALY; PET/CT compared with PET for ICER was £ 32,590 per QALY; and the ICER for PET/CT combined with conventional work-up versus PET/CT was £ 44,118. The package became more expensive with each additional diagnostic test added to PET and more effective in terms of QALYs gained. The conventional work-up was the preferred options as probabilistic sensitivity analysis showed at a willingness-to-pay threshold of £ 20,000 per QALY. Result of the current analysis suggested that the use of PET/CT in the diagnosis of esophageal cancer was unlikely to be cost-effective given the current willingness-to-pay thresholds that were accepted in the United Kingdom by decision-making bodies such as the National Institute for Health and Clinical Excellence.
format Article
author Azmi, Nor Aniza
Abdul Razak, Hairil Rashmizal
Vinjamuri, Sobhan
spellingShingle Azmi, Nor Aniza
Abdul Razak, Hairil Rashmizal
Vinjamuri, Sobhan
PET-CT in esophageal cancer management: a cost effectiveness analysis study
author_facet Azmi, Nor Aniza
Abdul Razak, Hairil Rashmizal
Vinjamuri, Sobhan
author_sort Azmi, Nor Aniza
title PET-CT in esophageal cancer management: a cost effectiveness analysis study
title_short PET-CT in esophageal cancer management: a cost effectiveness analysis study
title_full PET-CT in esophageal cancer management: a cost effectiveness analysis study
title_fullStr PET-CT in esophageal cancer management: a cost effectiveness analysis study
title_full_unstemmed PET-CT in esophageal cancer management: a cost effectiveness analysis study
title_sort pet-ct in esophageal cancer management: a cost effectiveness analysis study
publisher Universiti Teknologi Malaysia
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/81688/1/PET-CT%20in%20esophageal%20cancer.pdf
_version_ 1782759493833064448
score 12.935284

Similar Items