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Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies

Colorectal cancer (CRC) is one of the most common malignancies. In recent decades, early diagnosis and conventional therapies have resulted in a significant reduction in mortality. However, late stage metastatic disease still has very limited effective treatment options. There is a growing interest...

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Asıl Yazarlar: Chin, Liang Lee, Veeramani, Sanggeetha, Molouki, Aidin, Swee, Hua Erin Lim, Thomas, Warren, Suet, Lin Chia, Yusoff, Khatijah
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Online Erişim:http://psasir.upm.edu.my/id/eprint/82723/1/Virotherapy.pdf
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id oai:psasir.upm.edu.my:82723
record_format eprints
spelling oai:psasir.upm.edu.my:82723 http://psasir.upm.edu.my/id/eprint/82723/ Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies Chin, Liang Lee Veeramani, Sanggeetha Molouki, Aidin Swee, Hua Erin Lim Thomas, Warren Suet, Lin Chia Yusoff, Khatijah Colorectal cancer (CRC) is one of the most common malignancies. In recent decades, early diagnosis and conventional therapies have resulted in a significant reduction in mortality. However, late stage metastatic disease still has very limited effective treatment options. There is a growing interest in using viruses to help target therapies to tumour sites. In recent years the evolution of immunotherapy has emphasised the importance of directing the immune system to eliminate tumour cells; we aim to give a state-of-the-art over-view of the diverse viruses that have been investigated as potential oncolytic agents for the treatment of CRC. Taylor & Francis 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/82723/1/Virotherapy.pdf Chin, Liang Lee and Veeramani, Sanggeetha and Molouki, Aidin and Swee, Hua Erin Lim and Thomas, Warren and Suet, Lin Chia and Yusoff, Khatijah (2019) Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies. Cancer Investigation, 37 (8). pp. 393-414. ISSN 0735-7907; ESSN 1532-4192 https://www.tandfonline.com/doi/abs/10.1080/07357907.2019.1660887?journalCode=icnv20 10.1080/07357907.2019.1660887.
institution UPM IR
collection UPM IR
language English
description Colorectal cancer (CRC) is one of the most common malignancies. In recent decades, early diagnosis and conventional therapies have resulted in a significant reduction in mortality. However, late stage metastatic disease still has very limited effective treatment options. There is a growing interest in using viruses to help target therapies to tumour sites. In recent years the evolution of immunotherapy has emphasised the importance of directing the immune system to eliminate tumour cells; we aim to give a state-of-the-art over-view of the diverse viruses that have been investigated as potential oncolytic agents for the treatment of CRC.
format Article
author Chin, Liang Lee
Veeramani, Sanggeetha
Molouki, Aidin
Swee, Hua Erin Lim
Thomas, Warren
Suet, Lin Chia
Yusoff, Khatijah
spellingShingle Chin, Liang Lee
Veeramani, Sanggeetha
Molouki, Aidin
Swee, Hua Erin Lim
Thomas, Warren
Suet, Lin Chia
Yusoff, Khatijah
Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
author_facet Chin, Liang Lee
Veeramani, Sanggeetha
Molouki, Aidin
Swee, Hua Erin Lim
Thomas, Warren
Suet, Lin Chia
Yusoff, Khatijah
author_sort Chin, Liang Lee
title Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
title_short Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
title_full Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
title_fullStr Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
title_full_unstemmed Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
title_sort virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
publisher Taylor & Francis
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/82723/1/Virotherapy.pdf
_version_ 1819299820238536704
score 13.4562235

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