Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment
CpG-free pDNA was reported to facilitate sustained transgene expression with minimal inflammation in vivo as compared to CpG-containing pDNA. However, the expression potential and impact of CpG-free pDNA in in vitro model have never been described. Hence, in this study, we analyzed the transgene exp...
Saved in:
Main Authors: | Habib, Omar, M. Sakri, Rozita, Ghazalli, Nadiah, Chau, De Ming, Ling, King Hwa, Abdullah, Syahril |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science
2020
|
Online Access: | http://psasir.upm.edu.my/id/eprint/86578/1/Limited%20expression%20of%20non-integrating%20.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CpG-free plasmid DNA exhibits limited in vitro reporter gene expression due to transcriptional incongruity /
by: Muhammad Omar Habib Rahuman.
Published: (2017) -
CpG-free plasmid DNA exhibits limited in vitro reporter gene expression due to transcriptional incongruity
by: Habib Rahuman, Muhammad Omar
Published: (2017) -
CpG-free plasmid DNA exhibits limited in vitro reporter gene expression due to transcriptional incongruity
by: Habib Rahuman, Muhammad Omar
Published: (2017) -
Immunobiology of bacterial CpG-DNA /
Published: (2000) -
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
by: Hyde, Stephen C., et al.
Published: (2008)