An overview of the potential therapeutic applications of essential oils

The emergence of antimicrobial resistance (AMR) has urged researchers to explore therapeutic alternatives, one of which includes the use of natural plant products such as essential oils (EO). In fact, EO obtained from clove, oregano, thymus, cinnamon bark, rosemary, eucalyptus, and lavender have bee...

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Main Authors: Nasser Aljaafari, Mariam, AlAli, Asma Obaid, Baqais, Laila, Alqubaisy, Maream, AlAli, Mudhi, Molouki, Aidin, Abdullah, Janna Ong, Abushelaibi, Aisha, Lai, Kok-Song, Lim, Swee Hua Erin
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Published: Multidisciplinary Digital Publishing Institute 2021
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spelling oai:psasir.upm.edu.my:95881 http://psasir.upm.edu.my/id/eprint/95881/ An overview of the potential therapeutic applications of essential oils Nasser Aljaafari, Mariam AlAli, Asma Obaid Baqais, Laila Alqubaisy, Maream AlAli, Mudhi Molouki, Aidin Abdullah, Janna Ong Abushelaibi, Aisha Lai, Kok-Song Lim, Swee Hua Erin The emergence of antimicrobial resistance (AMR) has urged researchers to explore therapeutic alternatives, one of which includes the use of natural plant products such as essential oils (EO). In fact, EO obtained from clove, oregano, thymus, cinnamon bark, rosemary, eucalyptus, and lavender have been shown to present significant inhibitory effects on bacteria, fungi, and viruses; many studies have been done to measure EO efficacy against microorganisms. The strategy of combinatory effects via conventional and non-conventional methods revealed that the combined effects of EO-EO or EO-antibiotic exhibit enhanced efficacy. This paper aims to review the antimicrobial effects of EO, modes of EO action (membrane disruption, efflux inhibition, increase membrane permeability, and decrease in intracellular ATP), and their compounds' potential as effective agents against bacteria, fungi, and viruses. It is hoped that the integration of EO applications in this work can be used to consider EO for future clinical applications. Multidisciplinary Digital Publishing Institute 2021 Article PeerReviewed Nasser Aljaafari, Mariam and AlAli, Asma Obaid and Baqais, Laila and Alqubaisy, Maream and AlAli, Mudhi and Molouki, Aidin and Abdullah, Janna Ong and Abushelaibi, Aisha and Lai, Kok-Song and Lim, Swee Hua Erin (2021) An overview of the potential therapeutic applications of essential oils. Molecules, 26 (3). art. no. 628. pp. 1-27. ISSN 1420-3049 https://www.mdpi.com/1420-3049/26/3/628 10.3390/molecules26030628
institution UPM IR
collection UPM IR
description The emergence of antimicrobial resistance (AMR) has urged researchers to explore therapeutic alternatives, one of which includes the use of natural plant products such as essential oils (EO). In fact, EO obtained from clove, oregano, thymus, cinnamon bark, rosemary, eucalyptus, and lavender have been shown to present significant inhibitory effects on bacteria, fungi, and viruses; many studies have been done to measure EO efficacy against microorganisms. The strategy of combinatory effects via conventional and non-conventional methods revealed that the combined effects of EO-EO or EO-antibiotic exhibit enhanced efficacy. This paper aims to review the antimicrobial effects of EO, modes of EO action (membrane disruption, efflux inhibition, increase membrane permeability, and decrease in intracellular ATP), and their compounds' potential as effective agents against bacteria, fungi, and viruses. It is hoped that the integration of EO applications in this work can be used to consider EO for future clinical applications.
format Article
author Nasser Aljaafari, Mariam
AlAli, Asma Obaid
Baqais, Laila
Alqubaisy, Maream
AlAli, Mudhi
Molouki, Aidin
Abdullah, Janna Ong
Abushelaibi, Aisha
Lai, Kok-Song
Lim, Swee Hua Erin
spellingShingle Nasser Aljaafari, Mariam
AlAli, Asma Obaid
Baqais, Laila
Alqubaisy, Maream
AlAli, Mudhi
Molouki, Aidin
Abdullah, Janna Ong
Abushelaibi, Aisha
Lai, Kok-Song
Lim, Swee Hua Erin
An overview of the potential therapeutic applications of essential oils
author_facet Nasser Aljaafari, Mariam
AlAli, Asma Obaid
Baqais, Laila
Alqubaisy, Maream
AlAli, Mudhi
Molouki, Aidin
Abdullah, Janna Ong
Abushelaibi, Aisha
Lai, Kok-Song
Lim, Swee Hua Erin
author_sort Nasser Aljaafari, Mariam
title An overview of the potential therapeutic applications of essential oils
title_short An overview of the potential therapeutic applications of essential oils
title_full An overview of the potential therapeutic applications of essential oils
title_fullStr An overview of the potential therapeutic applications of essential oils
title_full_unstemmed An overview of the potential therapeutic applications of essential oils
title_sort overview of the potential therapeutic applications of essential oils
publisher Multidisciplinary Digital Publishing Institute
publishDate 2021
_version_ 1782761485644070912
score 12.935284