Mitochondrial DNA, Mitochondria, Disease and Stem Cells
This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication an...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2013.
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| Edition: | 1st ed. 2013. |
| Series: | Stem Cell Biology and Regenerative Medicine,
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| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-1-62703-101-1 |
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Table of Contents:
- Clinical Approach to the Diagnosis of Mitochondrial Disease
- Mitochondrial DNA Mutations and Their Effects on Complex I Biogenesis: Implications for Metabolic Disease
- Embryonic Stem Cells: A Signalling Perspective
- From Oocytes and Pluripotent Stem Cells to Fully Differentiated Fates: (Also) A Mitochondrial Odyssey
- From Pluripotency to Differentiation: The Role of mtDNA in Stem Cell Models of Mitochondrial Diseases
- The Role of Mitochondrial DNA in Tumor Cells
- Assisted Reproductive Technologies to Prevent the Transmission of mtDNA from one Generation to the Next.