Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin exper...
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2001
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oai:psasir.upm.edu.my:11224 http://psasir.upm.edu.my/id/eprint/11224/ Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep Ab. Hamid, Hasiah The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin experiment. Grazing on signal grass significantly decreased the concentration of cytochrome P-4S0 and the activity of drug metabolizing enzyme, viz. aminopyrine-N-demethylase, aniline-4- hydroxylase, UDP-glucuronyltransferase and glutathione-S-transferase in liver and kidney of sheep. The concentration of cytochrome P-4S0 was determined in microsomal fraction according to the method of Omura and Sato (1964a) as described by Mazel (1971). The activities of aminopyrine-N-demethylase and aniline-4- hydroxylase were determined using Mazel, 1971 method by estimating the 2001-02 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf Ab. Hamid, Hasiah (2001) Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep. Masters thesis, Universiti Putra Malaysia. English |
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UPM IR |
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English English |
| description |
The protective effect of phenobarbitone and griseofulvin against signal grass (B.
decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous
Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment
and twenty-seven animals were used in griseofulvin experiment. Grazing on signal
grass significantly decreased the concentration of cytochrome P-4S0 and the activity
of drug metabolizing enzyme, viz. aminopyrine-N-demethylase, aniline-4-
hydroxylase, UDP-glucuronyltransferase and glutathione-S-transferase in liver and
kidney of sheep. The concentration of cytochrome P-4S0 was determined in
microsomal fraction according to the method of Omura and Sato (1964a) as described
by Mazel (1971). The activities of aminopyrine-N-demethylase and aniline-4-
hydroxylase were determined using Mazel, 1971 method by estimating the |
| format |
Thesis |
| author |
Ab. Hamid, Hasiah |
| spellingShingle |
Ab. Hamid, Hasiah Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| author_facet |
Ab. Hamid, Hasiah |
| author_sort |
Ab. Hamid, Hasiah |
| title |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_short |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_full |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_fullStr |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_full_unstemmed |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_sort |
protective effect of phenorbarbitone and griseofulvin againt signal grass (brachiaria decumbens)toxiciti in sheep |
| publishDate |
2001 |
| url |
http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf |
| _version_ |
1819293523259686912 |
| score |
13.4562235 |