תמונות העטיפה

Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)

The phosphanegold(I) thiocarbamides, Ph3PAu{SC(OR)=NC6H4Me-4} for R = Me (1), Et (2) and iPr (3), have been shown to have essentially linear gold atom coordination geometries defined by phosphane-P and thiolate-S atoms, and exhibit minimum inhibitory concentration (MIC) values in the range of 1–37 μ...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yeo, Chien Ing, Sim, Jiun Horng, Khoo, Chai Hoon, Goh, Zheng Jie, Ang, Kok Pian, Cheah, Yoke Kqueen, Fairuz, Zainal Abidin, Abdul Halim, Siti Nadiah, Ng, Seik Weng, Seng, Hoi Ling, Tiekink, Edward R. T.
פורמט: Article
שפה:English
יצא לאור: Springer 2013
גישה מקוונת:http://psasir.upm.edu.my/id/eprint/29592/1/Pathogenic%20Gram-positive%20bacteria%20are%20highly%20sensitive%20to%20triphenylphosphanegold%28O-alkylthiocarbamates%29%2C%20Ph3PAu%5BSC%28OR%29%3DN%28p-tolyl%29%5D%20%28R%E2%80%89%3D%E2%80%89Me%2C%20Et%20and%20iPr%29.pdf
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
id oai:psasir.upm.edu.my:29592
record_format eprints
spelling oai:psasir.upm.edu.my:29592 http://psasir.upm.edu.my/id/eprint/29592/ Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr) Yeo, Chien Ing Sim, Jiun Horng Khoo, Chai Hoon Goh, Zheng Jie Ang, Kok Pian Cheah, Yoke Kqueen Fairuz, Zainal Abidin Abdul Halim, Siti Nadiah Ng, Seik Weng Seng, Hoi Ling Tiekink, Edward R. T. The phosphanegold(I) thiocarbamides, Ph3PAu{SC(OR)=NC6H4Me-4} for R = Me (1), Et (2) and iPr (3), have been shown to have essentially linear gold atom coordination geometries defined by phosphane-P and thiolate-S atoms, and exhibit minimum inhibitory concentration (MIC) values in the range of 1–37 μg/ml against four Gram-positive bacteria, namely Bacillus cereus, Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus; compounds 1–3 are less potent against a broad panel of 16 Gram-negative bacteria. As the minimum bactericidal concentration values were quite similar to the MIC values, compounds 1–3 are effective bactericidal agents. The specific action against the four Gram-positive bacteria suggests they function by inhibition of peptidoglycan synthesis. Springer 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29592/1/Pathogenic%20Gram-positive%20bacteria%20are%20highly%20sensitive%20to%20triphenylphosphanegold%28O-alkylthiocarbamates%29%2C%20Ph3PAu%5BSC%28OR%29%3DN%28p-tolyl%29%5D%20%28R%E2%80%89%3D%E2%80%89Me%2C%20Et%20and%20iPr%29.pdf Yeo, Chien Ing and Sim, Jiun Horng and Khoo, Chai Hoon and Goh, Zheng Jie and Ang, Kok Pian and Cheah, Yoke Kqueen and Fairuz, Zainal Abidin and Abdul Halim, Siti Nadiah and Ng, Seik Weng and Seng, Hoi Ling and Tiekink, Edward R. T. (2013) Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr). Gold Bulletin, 46 (3). pp. 145-152. ISSN 2364-821X; ESSN: 2190-7579 http://link.springer.com/article/10.1007/s13404-013-0091-z?view=classic 10.1007/s13404-013-0091-z
institution UPM IR
collection UPM IR
language English
description The phosphanegold(I) thiocarbamides, Ph3PAu{SC(OR)=NC6H4Me-4} for R = Me (1), Et (2) and iPr (3), have been shown to have essentially linear gold atom coordination geometries defined by phosphane-P and thiolate-S atoms, and exhibit minimum inhibitory concentration (MIC) values in the range of 1–37 μg/ml against four Gram-positive bacteria, namely Bacillus cereus, Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus; compounds 1–3 are less potent against a broad panel of 16 Gram-negative bacteria. As the minimum bactericidal concentration values were quite similar to the MIC values, compounds 1–3 are effective bactericidal agents. The specific action against the four Gram-positive bacteria suggests they function by inhibition of peptidoglycan synthesis.
format Article
author Yeo, Chien Ing
Sim, Jiun Horng
Khoo, Chai Hoon
Goh, Zheng Jie
Ang, Kok Pian
Cheah, Yoke Kqueen
Fairuz, Zainal Abidin
Abdul Halim, Siti Nadiah
Ng, Seik Weng
Seng, Hoi Ling
Tiekink, Edward R. T.
spellingShingle Yeo, Chien Ing
Sim, Jiun Horng
Khoo, Chai Hoon
Goh, Zheng Jie
Ang, Kok Pian
Cheah, Yoke Kqueen
Fairuz, Zainal Abidin
Abdul Halim, Siti Nadiah
Ng, Seik Weng
Seng, Hoi Ling
Tiekink, Edward R. T.
Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
author_facet Yeo, Chien Ing
Sim, Jiun Horng
Khoo, Chai Hoon
Goh, Zheng Jie
Ang, Kok Pian
Cheah, Yoke Kqueen
Fairuz, Zainal Abidin
Abdul Halim, Siti Nadiah
Ng, Seik Weng
Seng, Hoi Ling
Tiekink, Edward R. T.
author_sort Yeo, Chien Ing
title Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_short Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_full Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_fullStr Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_full_unstemmed Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_sort pathogenic gram-positive bacteria are highly sensitive to triphenylphosphanegold(o-alkylthiocarbamates), ph3pau[sc(or)=n(p-tolyl)] (r = me, et and ipr)
publisher Springer
publishDate 2013
url http://psasir.upm.edu.my/id/eprint/29592/1/Pathogenic%20Gram-positive%20bacteria%20are%20highly%20sensitive%20to%20triphenylphosphanegold%28O-alkylthiocarbamates%29%2C%20Ph3PAu%5BSC%28OR%29%3DN%28p-tolyl%29%5D%20%28R%E2%80%89%3D%E2%80%89Me%2C%20Et%20and%20iPr%29.pdf
_version_ 1782720480373899264
score 12.933938

פריטים דומים