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Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla

Probit analysis is generally employed in the studies of toxicology, to determine the concentration of toxicant causing 50% mortality or LC50 value. The response of an organism is generally binomial and is typically sigmoidal in property. The Probit value can be calculated by hand or can be calculate...

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Main Authors: Halmi, Mohd. Izuan Effendi, Abd Rahim, Mohd. Badrin Hanizam, Othman, Ahmad Razi
Format: Article
Language:English
Published: Hibiscus Publisher 2018
Online Access:http://psasir.upm.edu.my/id/eprint/72616/1/Estimation%20of%20LC50%20.pdf
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spelling oai:psasir.upm.edu.my:72616 http://psasir.upm.edu.my/id/eprint/72616/ Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla Halmi, Mohd. Izuan Effendi Abd Rahim, Mohd. Badrin Hanizam Othman, Ahmad Razi Probit analysis is generally employed in the studies of toxicology, to determine the concentration of toxicant causing 50% mortality or LC50 value. The response of an organism is generally binomial and is typically sigmoidal in property. The Probit value can be calculated by hand or can be calculated through the use of a computer via software, the latter utilising the maximum likelihood method which is a more precise estimation of the parameters. When a published result failed to produce the 95% confidence interval, the results can be re-evaluated using software including SPSS. In this study, the LC50 value of the effect of ferrous sulphate to the fish Catla catla is re-evaluated using the Probit modelling exercise via the SPSS software, which gave an LC50 value of 8.271 p.p.m., with a 95% confidence interval from 7.353 to 9.189 p.p.m. The sub lethal concentration (SLC) for ferrous sulphate, which is one fourth of the LC50 value was 2.06 p.p.m. Hibiscus Publisher 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/72616/1/Estimation%20of%20LC50%20.pdf Halmi, Mohd. Izuan Effendi and Abd Rahim, Mohd. Badrin Hanizam and Othman, Ahmad Razi (2018) Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla. Journal of Environmental Microbiology and Toxicology, 6 (1). 21 - 23. ISSN 2289-5906 https://journal.hibiscuspublisher.com/index.php/JEMAT/article/view/402
institution UPM IR
collection UPM IR
language English
description Probit analysis is generally employed in the studies of toxicology, to determine the concentration of toxicant causing 50% mortality or LC50 value. The response of an organism is generally binomial and is typically sigmoidal in property. The Probit value can be calculated by hand or can be calculated through the use of a computer via software, the latter utilising the maximum likelihood method which is a more precise estimation of the parameters. When a published result failed to produce the 95% confidence interval, the results can be re-evaluated using software including SPSS. In this study, the LC50 value of the effect of ferrous sulphate to the fish Catla catla is re-evaluated using the Probit modelling exercise via the SPSS software, which gave an LC50 value of 8.271 p.p.m., with a 95% confidence interval from 7.353 to 9.189 p.p.m. The sub lethal concentration (SLC) for ferrous sulphate, which is one fourth of the LC50 value was 2.06 p.p.m.
format Article
author Halmi, Mohd. Izuan Effendi
Abd Rahim, Mohd. Badrin Hanizam
Othman, Ahmad Razi
spellingShingle Halmi, Mohd. Izuan Effendi
Abd Rahim, Mohd. Badrin Hanizam
Othman, Ahmad Razi
Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla
author_facet Halmi, Mohd. Izuan Effendi
Abd Rahim, Mohd. Badrin Hanizam
Othman, Ahmad Razi
author_sort Halmi, Mohd. Izuan Effendi
title Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla
title_short Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla
title_full Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla
title_fullStr Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla
title_full_unstemmed Estimation of LC50 and its confidence interval for the effect of ferrous sulphate on Catla catla
title_sort estimation of lc50 and its confidence interval for the effect of ferrous sulphate on catla catla
publisher Hibiscus Publisher
publishDate 2018
url http://psasir.upm.edu.my/id/eprint/72616/1/Estimation%20of%20LC50%20.pdf
_version_ 1819299055522545664
score 13.4562235

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