Pancreatic cancer treatment with targeted therapies: are we there yet

by Nwaefulu, O. Ngozi, Sagineedu, S. Rao, Islam, M. Kaisarul, Stanslas, J.
Published 2022

Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review

by Bagalkotkar, Gururaj, Sagineedu, Sreenivasa Rao, Saad, Mohd Said, Stanslas, Johnson
Published 2006

SRJ09, a promising anticancer drug lead: elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy

by Wong, Charng Choon, Lim, Siang Hui, Sagineedu, Sreenivasa Rao, Lajis, Nordin, Stanslas, Johnson
Published 2016

Andrographolide as a template in the synthesis of new anticancer agents with potentially novel molecular targets

by Stanslas, Johnson, Lim, Siang Hui, Wong, Charng Choon, Sagineedu, Sreenivasa Rao, Lajis, Nordin
Published 2010

Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells.

by Hui, Chyn Wong, Sagineedu, Sreenivasa Rao, Lajis, Md. Nordin, Loke, Seng Cheong, Stanslas, Johnson
Published 2011

More than just a KRAS inhibitor: DCAI abrogates the self-renewal of pancreatic cancer stem cells in vitro

by Yuan, Han Teh, Rui, Jing, Ramasamy, Rajesh, Kok, Lian Ho, Sagineedu, Sreenivasa Rao, Stanslas, Johnson
Published 2023

SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells

by Wong, Hui Chyn, Wong, Charng Choon, Sagineedu, Sreenivasa Rao, Loke, Seng Cheong, Lajis, Nordin, Stanslas, Johnson
Published 2014

Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents

by Soo, Hon Liong, Quah, Shun Ying, Sulaiman, Ibrahim, Sagineedu, Sreenivasa Rao, Lim, Chee Woei, Stanslas, Johnson
Published 2019

SRS06, a new semisynthetic andrographolide derivative with improved anticancer potency and selectivity, inhibits nuclear factor-kB nuclear binding in the A549 non-small cell lung c...

by Lim, Jonathan Chee Woei, Jeyaraj, Ethel Jeyaseela, Sagineedu, Sreenivasa Rao, Wong, Wai Shiu Fred, Stanslas, Johnson
Published 2015

Pharmacological modulation of apoptosis and autophagy in pancreatic cancer treatment

by Stanslas, Johnson, Islam, Mohammad Kaisarul, Selvarajoo, Nityaa, Sagineedu, Sreenivasa Rao, Lian, Ho Kok, Lim, Jonathan Chee Woei
Published 2022

NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide

by Wong, Charng Choon, Sagineedu, Sreenivasa Rao, Sumon, Shariful Hasan, Mohamad Sidik, Shiran, Phillips, Roger, Lajis, Nordin, Stanslas, Johnson
Published 2014

A classical genetic solution to enhance the biosynthesis of anticancer phytochemicals in Andrographis paniculata nees

by Valdiani, Alireza, Talei, Daryush, Tan, Soon Guan, Abdul Kadir, Mihdzar, Mahmood, Maziah, Yusop, Mohd Rafii, Sagineedu, Sreenivasa Rao
Published 2014

In silico and saturation transfer difference NMR approaches to unravel the binding mode of an andrographolide derivative to K-Ras oncoprotein

by Shun, Ying Quah, Tan, Michelle Siying, Kok, Lian Ho, Abd Manan, Nizar, Gorfe, Alemayehu A., Deb, Pran Kishore, Sagineedu, Sreenivasa Rao, Stanslas, Johnson
Published 2020

Microarray-based identification of differentially expressed genes associated with andrographolide derivatives-induced resistance in colon and prostate cancer cell lines

by Shun, Ying Quah, Charng, Choon Wong, Hui, Chyn Wong, Ho, Kok Lian, Abdul Manan, Nizar, Deb, Pran Kishore, Sagineedu, Sreenivasa Rao, Stanslas, Johnson
Published 2021

In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog

by Wong, Charng Choon, Periasamy, Nagarajan, Sagineedu, Sreenivasa Rao, Mohd Sidik, Shiran, Sumon, Md. Shariful Hasan, Loadman, Paul, Phillips, Roger, Lajis, Md. Nordin, Stanslas, Johnson
Published 2014

Prevalence of macrolide resistance and in vitro activities of six antimicrobial agents against clinical isolates of streptococcus pneumoniae from a multi-center surveillance in Mal...

by Jeevajothi Nathan, Jayakayatri, Mohd Taib, Niazlin, Mohd Desa, Mohd Nasir, Masri, Siti Norbaya, Md Yasin, Rohani, Jamal, Farida Fatema @ Farida, Sagineedu, Sreenivasa Rao, Karunanidhi, Arunkumar
Published 2013

Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function

by Hocker, Harrison J., Cho, Kwang Jin, Chen, Chung Ying K., Rambahal, Nandini, Sagineedu, Sreenivasa Rao, Shaari, Khozirah, Stanslas, Johnson, Hancock, John F., Gorfe, Alemayehu A.
Published 2013

The impact of cycleanine in cancer research: a computational study

by Nwaefulu, Ogochukwu Ngozi, Al-Shar'i, Nizar A, Owolabi, Josephine Omonkhelin, Sagineedu, Sreenivasa Rao, Lim, Chee Woei, Lam, Kok Wai, Islam, Mohammad Kaisarul, Jayanthi, Sivaraman, Stanslas, Johnson
Published 2022