Cover Image

Anti-inflammatory and anti-cancer activity of Theobroma cacao

Anti-inflammatory activity of the testa and anti-cancer activity of the pods of Theobroma cacao was investigated using the tetradecanoyphorbol acetate (TPA)-induced ear oedema model and Trypan blue assay against nasopharyngeal cancer cell Jines. It was found that the ethyl acetate and methanol extra...

Full description

Saved in:
Bibliographic Details
Main Authors: Zainal B., Mohd. Razip A., Nurul Huda M., Mohd. Shahrin S.
Format: Proceedings Paper
Language:English
Published: Malaysian Cocoa Board 2015
Subjects:
THEOBROMA CACAO
TESTA
FRUIT
EXTRACTS
HUMAN DISEASES
NEOPLASMS
ANTIINFLAMMATORY AGENTS
MALAYSIA
EXTRAIT
MALADIE DE L'HOMME
NEOPLASME
ANTI-INFLAMMATOIRE
MALAISIE
FRUTO
EXTRACTOS
ENFERMEDADES HUMANAS
NEOPLASMAS
ANTINFLAMATORIOS
MALASIA
http://www.fao.org/aos/agrovoc#c_7713
http://www.fao.org/aos/agrovoc#c_7681
http://www.fao.org/aos/agrovoc#c_3119
http://www.fao.org/aos/agrovoc#c_2767
http://www.fao.org/aos/agrovoc#c_29198
http://www.fao.org/aos/agrovoc#c_5122
http://www.fao.org/aos/agrovoc#c_507
http://www.fao.org/aos/agrovoc#c_4533
Online Access:http://agris.upm.edu.my:8080/dspace/handle/0/9490
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Anti-inflammatory activity of the testa and anti-cancer activity of the pods of Theobroma cacao was investigated using the tetradecanoyphorbol acetate (TPA)-induced ear oedema model and Trypan blue assay against nasopharyngeal cancer cell Jines. It was found that the ethyl acetate and methanol extracts of the testa of Theobroma cacao displayed inhibitory effect of more than 75% at concentration of 2.0 mg per ear of both extracts. The anti-cancer assay of methanol extract of the pods of Theobroma cacao exhibited significant inhibitory activity against the nasopharyngeal cancer cell lines at the concentration of 0.1 and 1.0 mug/ml after 48 hours incubation.

Similar Items