Anti-inflammatory and anti-cancer activity of Theobroma cacao

Anti-inflammatory activity of the testa and anti-cancer activity of the pods of Theobroma cacao was investigated using the tetradecanoyphorbol acetate (TPA)-induced ear oedema model and Trypan blue assay against nasopharyngeal cancer cell Jines. It was found that the ethyl acetate and methanol extra...

Full description

Saved in:
Bibliographic Details
Main Authors: Zainal B., Mohd. Razip A., Nurul Huda M., Mohd. Shahrin S.
Format: Proceedings Paper
Language:English
Published: Malaysian Cocoa Board 2015
Subjects:
Online Access:http://agris.upm.edu.my:8080/dspace/handle/0/9490
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:http:--agris.upm.edu.my:0-9490
record_format dspace
spelling oai:http:--agris.upm.edu.my:0-9490Anti-inflammatory and anti-cancer activity of Theobroma cacaoZainal B.Mohd. Razip A.Nurul Huda M.Mohd. Shahrin S.THEOBROMA CACAOTESTAFRUITEXTRACTSHUMAN DISEASESNEOPLASMSANTIINFLAMMATORY AGENTSMALAYSIATHEOBROMA CACAOTESTAFRUITEXTRAITMALADIE DE L'HOMMENEOPLASMEANTI-INFLAMMATOIREMALAISIETHEOBROMA CACAOTESTAFRUTOEXTRACTOSENFERMEDADES HUMANASNEOPLASMASANTINFLAMATORIOSMALASIAhttp://www.fao.org/aos/agrovoc#c_7713http://www.fao.org/aos/agrovoc#c_7681http://www.fao.org/aos/agrovoc#c_3119http://www.fao.org/aos/agrovoc#c_2767http://www.fao.org/aos/agrovoc#c_29198http://www.fao.org/aos/agrovoc#c_5122http://www.fao.org/aos/agrovoc#c_507http://www.fao.org/aos/agrovoc#c_4533Anti-inflammatory activity of the testa and anti-cancer activity of the pods of Theobroma cacao was investigated using the tetradecanoyphorbol acetate (TPA)-induced ear oedema model and Trypan blue assay against nasopharyngeal cancer cell Jines. It was found that the ethyl acetate and methanol extracts of the testa of Theobroma cacao displayed inhibitory effect of more than 75% at concentration of 2.0 mg per ear of both extracts. The anti-cancer assay of methanol extract of the pods of Theobroma cacao exhibited significant inhibitory activity against the nasopharyngeal cancer cell lines at the concentration of 0.1 and 1.0 mug/ml after 48 hours incubation.Malaysian Cocoa BoardKota Kinabalu, Sabah, Malaysia2015-06-26T07:39:56Z2015-06-26T07:39:56Z2007Proceedings PaperArticleNon-RefereedProceedings 2007 Conference on Plantation Commodities: Visionary Agriculture: Malaysian Commodity Crops in 100 Years: Kuala Lumpur (Malaysia), 3-4 Jul 2007, p. 249-252http://agris.upm.edu.my:8080/dspace/handle/0/9490MY2011050433enhttp://www.oceandocs.org/license
institution AGRIS
collection AGRIS
language English
topic THEOBROMA CACAO
TESTA
FRUIT
EXTRACTS
HUMAN DISEASES
NEOPLASMS
ANTIINFLAMMATORY AGENTS
MALAYSIA
THEOBROMA CACAO
TESTA
FRUIT
EXTRAIT
MALADIE DE L'HOMME
NEOPLASME
ANTI-INFLAMMATOIRE
MALAISIE
THEOBROMA CACAO
TESTA
FRUTO
EXTRACTOS
ENFERMEDADES HUMANAS
NEOPLASMAS
ANTINFLAMATORIOS
MALASIA
http://www.fao.org/aos/agrovoc#c_7713
http://www.fao.org/aos/agrovoc#c_7681
http://www.fao.org/aos/agrovoc#c_3119
http://www.fao.org/aos/agrovoc#c_2767
http://www.fao.org/aos/agrovoc#c_29198
http://www.fao.org/aos/agrovoc#c_5122
http://www.fao.org/aos/agrovoc#c_507
http://www.fao.org/aos/agrovoc#c_4533
spellingShingle THEOBROMA CACAO
TESTA
FRUIT
EXTRACTS
HUMAN DISEASES
NEOPLASMS
ANTIINFLAMMATORY AGENTS
MALAYSIA
THEOBROMA CACAO
TESTA
FRUIT
EXTRAIT
MALADIE DE L'HOMME
NEOPLASME
ANTI-INFLAMMATOIRE
MALAISIE
THEOBROMA CACAO
TESTA
FRUTO
EXTRACTOS
ENFERMEDADES HUMANAS
NEOPLASMAS
ANTINFLAMATORIOS
MALASIA
http://www.fao.org/aos/agrovoc#c_7713
http://www.fao.org/aos/agrovoc#c_7681
http://www.fao.org/aos/agrovoc#c_3119
http://www.fao.org/aos/agrovoc#c_2767
http://www.fao.org/aos/agrovoc#c_29198
http://www.fao.org/aos/agrovoc#c_5122
http://www.fao.org/aos/agrovoc#c_507
http://www.fao.org/aos/agrovoc#c_4533
Zainal B.
Mohd. Razip A.
Nurul Huda M.
Mohd. Shahrin S.
Anti-inflammatory and anti-cancer activity of Theobroma cacao
description Anti-inflammatory activity of the testa and anti-cancer activity of the pods of Theobroma cacao was investigated using the tetradecanoyphorbol acetate (TPA)-induced ear oedema model and Trypan blue assay against nasopharyngeal cancer cell Jines. It was found that the ethyl acetate and methanol extracts of the testa of Theobroma cacao displayed inhibitory effect of more than 75% at concentration of 2.0 mg per ear of both extracts. The anti-cancer assay of methanol extract of the pods of Theobroma cacao exhibited significant inhibitory activity against the nasopharyngeal cancer cell lines at the concentration of 0.1 and 1.0 mug/ml after 48 hours incubation.
format Proceedings Paper
author Zainal B.
Mohd. Razip A.
Nurul Huda M.
Mohd. Shahrin S.
author_facet Zainal B.
Mohd. Razip A.
Nurul Huda M.
Mohd. Shahrin S.
author_sort Zainal B.
title Anti-inflammatory and anti-cancer activity of Theobroma cacao
title_short Anti-inflammatory and anti-cancer activity of Theobroma cacao
title_full Anti-inflammatory and anti-cancer activity of Theobroma cacao
title_fullStr Anti-inflammatory and anti-cancer activity of Theobroma cacao
title_full_unstemmed Anti-inflammatory and anti-cancer activity of Theobroma cacao
title_sort anti-inflammatory and anti-cancer activity of theobroma cacao
publisher Malaysian Cocoa Board
publishDate 2015
url http://agris.upm.edu.my:8080/dspace/handle/0/9490
_version_ 1819284259953704960
score 13.4562235